Predictors of One-Year Outcomes after Percutaneous Coronary Interventions in Octogenarian Patients with Acute Coronary Syndrome

Abstract

This work investigates the long-term outcomes of coronary stenting and predictors of two-year outcomes in octogenarian patients with acute coronary syndrome. A total of 406 patients with STEMI, NSTEMI and unstable angina undergoing percutaneous coronary intervention (PCI) were included in the study. We assessed the results at a median follow up of 20 months, from 1 year to 3 years. In-hospital mortality in the group of patients older than 80 was 8% and the long-term mortality was 21%. Cardiogenic shock, multi-vessel coronary disease, ejection fraction less than 35, and left main coronary artery lesion were independent predictors of long-term mortality. The best prognosis corresponded to those of drug eluting stents use, radial approach and GP IIb/IIIa use in patients with ST-segment elevation myocardial infarction. The progression of cardiac and renal failure was the main cause of death during this period. Our results suggested that percutaneous coronary interventions in octogenarian patients with acute coronary syndrome were associated with good clinical and long-term outcomes. DES use, radial approach and GP IIb/IIIa use in patients with ST-segment elevation myocardial infarction were associated with improved all-cause mortality in our population.