Email this article Possible Approaches to Increase the Longevity of Experimental Animals
- Authors: Kulikov A.V.1, Arkhipova L.V.1, Kulikova P.A.2, Glazkov A.A.2, Kulikov D.A.2
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Affiliations:
- Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences
- Vladimirsky Moscow Regional Research and Clinical Institute
- Issue: Vol 8, No 4 (2018)
- Pages: 271-276
- Section: Article
- URL: https://journals.rcsi.science/2079-0570/article/view/206000
- DOI: https://doi.org/10.1134/S2079057018040100
- ID: 206000
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Abstract
A statistically significant difference in the cumulative survival of Wistar rats born in different seasons has been shown: animals born in late November–early December had an average lifespan 24.8% longer, a minimum lifespan 14.3% longer, and a maximum lifespan 20.7% longer in comparison with animals born in April. Transplantation of thymus tissue into the immune privileged anterior chamber of the eye in animals born both in November and April has shown a geroprotective effect.
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About the authors
A. V. Kulikov
Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences
Author for correspondence.
Email: 29.04.55@mail.ru
Russian Federation, Pushchino, Moscow oblast, 142290
L. V. Arkhipova
Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences
Email: 29.04.55@mail.ru
Russian Federation, Pushchino, Moscow oblast, 142290
P. A. Kulikova
Vladimirsky Moscow Regional Research and Clinical Institute
Email: 29.04.55@mail.ru
Russian Federation, Moscow, 129110
A. A. Glazkov
Vladimirsky Moscow Regional Research and Clinical Institute
Email: 29.04.55@mail.ru
Russian Federation, Moscow, 129110
D. A. Kulikov
Vladimirsky Moscow Regional Research and Clinical Institute
Email: 29.04.55@mail.ru
Russian Federation, Moscow, 129110
