Influence of Bone Marrow Autotransplantation on the Neurotransmitter Structures of appendix vermiformis in Old Rats

Abstract

The influence of bone marrow autotransplantation on neurotransmitter structures of appendix vermiformis was studied. The investigation revealed that an increase in the number of neurotransmitter structures (mast and granular luminescent cells) with a high content of catecholamines and serotonin was noted in old rats 40 min after bone marrow autotransplantation. Cellular differentiations with a high neuroamine content were found in the reproductive center of appendix vermiformis lymphoid-nodes. Two hours after bone marrow autotransplantation, their number decreased and the content of catecholamines and serotonin decreased as well. The immunohistochemical reaction showed an increase in cellular proliferative activity, both in proper t. mucosa plate crypts and appendix vermiformis lymphoid nodules, up to 40 min of the experiment. After 2 h, Ki-67 positive cells decreased both in t. mucosa and t. s/mucosa of appendix vermiformis.