The telomere-telomerase system and mental processes in aging, norm and pathology (Literature review)


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Abstract

This literature review presents results of research showing relationships between the functional activity of the telomere-telomerase system and mental (cognitive and emotional) processes in normal and various pathological states: chronic stress, depression, bipolar disorder, schizophrenia, mild cognitive impairment, and dementia in aging. It also refers to age-specific, environmental (psycho-social, economic), immunological, and genetic and epigenetic factors that influence these relationships.

About the authors

K. I. Pavlov

Institute of Experimental Medicine

Author for correspondence.
Email: youngexp@yandex.ru
Russian Federation, St. Petersburg, 197376

V. N. Mukhin

Institute of Experimental Medicine

Email: youngexp@yandex.ru
Russian Federation, St. Petersburg, 197376

V. M. Klimenko

Institute of Experimental Medicine

Email: youngexp@yandex.ru
Russian Federation, St. Petersburg, 197376

V. N. Anisimov

Petrov Research Institute of Oncology

Email: youngexp@yandex.ru
Russian Federation, St. Petersburg, 197758


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