Stochastic simulation model for matching the ages of laboratory animals (mammals) and humans

Abstract

The paper proposes a simple approach for matching the ages of humans and mammals (some laboratory animals are considered to be mammals). A mathematical and simulation model has been built based on an analysis of the time of the onset of individual ontogenic events (such as the emergence of the first molars, first ovulation, almost complete cessation of growth, and menopause for female individuals). The choice of the these events is due to the fact that the time of the onset of the same events can be individually fixed in the human. Age-matching is important in giving each person the opportunity to make an individual choice in the regulation of a drug application that corresponds to his or her biological age.