Case report of Hashimoto encephalopathy in a 21-year-old female patient

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Abstract

Hashimoto encephalopathy is a rarely diagnosed autoimmune neurological disorder, associated with the presence of antithyroid antibodies. The variability of clinical presentation, rarity of the disease, and absence of specific diagnostic markers make timely diagnosis very complicated. This article describes a clinical case of a female patient with Hashimoto encephalopathy and discusses diagnosis, differential diagnosis and treatment approaches. We emphasize the importance of establishing a timely diagnosis, considering high efficacy of targeted treatment.

About the authors

Tatiana E. Popova

Yakut Research Center of the Complex Medical Problems

Author for correspondence.
Email: tata2504@yandex.ru
ORCID iD: 0000-0003-1062-1540

D. Sci. (Med.), Deputy director for science

Russian Federation, Yakutsk

Alexey A. Tappakhov

Yakut Research Center of the Complex Medical Problems; M.K. Ammosov North-Eastern Federal University

Email: tata2504@yandex.ru
ORCID iD: 0000-0002-4159-500X

Cand. Sci. (Med.), senior lecturer, Neurology and psychiatry department, senior researcher, Laboratory of neuropsychophysiological research, Medical Institute, senior researcher, Laboratory of neurodegenerative diseases

Russian Federation, Yakutsk; Yakutsk

Tatiana K. Davydova

Yakut Research Center of the Complex Medical Problems

Email: tata2504@yandex.ru
ORCID iD: 0000-0001-9525-1512

Cand. Sci. (Med.), leading researcher, Laboratoryof neurodegenerative diseases

Russian Federation, Yakutsk

Tatiana G. Govorova

M.K. Ammosov North-Eastern Federal University

Email: tata2504@yandex.ru
ORCID iD: 0000-0003-0610-3660

postgraduate student, Department of neurology and psychiatry, Head, Laboratory of neuropsychophysiological research, Medical Institute

Russian Federation, Yakutsk

Alyona Yu. Petrova

Republican Hospital No. 2 — The center of the Emergency Medical Care

Email: tata2504@yandex.ru

neurologist, Department of neurology

Russian Federation, Yakutsk

Alina E. Adamova

Yakut Research Center of the Complex Medical Problems

Email: tata2504@yandex.ru
ORCID iD: 0000-0002-6518-0079

neurologist, junior researcher, Laboratory of neurodegenerative diseases

Russian Federation, Yakutsk

Anna E. Steblevskaya

M.K. Ammosov North-Eastern Federal University

Email: tata2504@yandex.ru

neurologist, Department of internal medicine and general practice, Medical Institute, Faculty of Postgraduate Training of Physicians

Russian Federation, Yakutsk

References

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Supplementary files

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1. JATS XML
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2. Fig. 1. Fragment of video EEG monitoring of patient A. Hypersynchronous α rhythm with a frequency of 10 Hz and an amplitude of up to 80 µV is observed. There was no epileptiform activity during the recording.

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3. Fig. 2. A fragment of right arm tremorography during a study of the kinetic component of tremor. Electrodes are positioned over the flexor carpi ulnaris and the extensor carpi radialis muscles: А - before treatment; В - after treatment.

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Copyright (c) 2021 Popova T.E., Tappakhov A.A., Davydova T.K., Govorova T.G., Petrova A.Y., Adamova A.E., Steblevskaya A.E.

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This work is licensed under a Creative Commons Attribution 4.0 International License.

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