Complex approach to the treatment of patients with non-valvular atrial fibrillation. Place rivaroхaban

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Abstract

Atrial fibrillation (AF) is the most common heart rhythm disorder associated with aging. Diagnosis of AF requires documentation of the typical electrocardiogram pattern registration. Diagnosis of AF before complications is a recognized priority in the prevention of cardioembolic stroke. Non-valvular atrial fibrillation increases the risk of stroke by three to five times, especially in elderly patients, creating a significant load on the health care system, negatively affects the quality of life of patients. The basic principles of the supervision of patients with AF: emergency control of the frequency and/or rhythm to ensure stable hemodynamics and symptom relief; assessment and correction of factors contributing to the development, maintenance and recurrence of AF; assessment of the thromboembolic complications risk (stroke) and the anticoagulant therapy appointment. The use of oral anticoagulants is indicated in all patients with non-valvular AF, except for patients with low risk of stroke on the basis of the CHA2DS2-VASc scale or in the presence of absolute contraindications to anticoagulant therapy. Currently, there are research data illustrating the relative advantages of representatives of the new subclass of oral anticoagulants, for example, highly selective direct inhibitor of factor XA - rivaroxaban (Xarelto), which has a number of clinical and practical advantages over standard therapy in the treatment of elderly patients with non-valvular AF.

About the authors

Tatiana E. Morozova

I.M. Sechenov First Moscow State Medical University (Sechenov University)

Email: temorozova@gmail.com
D. Sci. (Med.), Prof. Moscow, Russia

Natalia A. Konyshko

I.M. Sechenov First Moscow State Medical University (Sechenov University)

D. Sci. (Med.) Moscow, Russia

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