Violations of purine metabolism and their correction. The urologist's point of view

In the article in the form of clinical lecture, disorders of purine metabolism, their clinical forms, pathogenesis, peculiarities of laboratory diagnostics and medicamentous correction with inhibitors of xanthine oxidase (allopurinolum, febuxostat) are considered. From the position of the urologist, the specifics of citrate litholytic therapy and metaphylactics of urate nephrolithiasis with regard to hyperuricemia, the administration of inhibitors of xanthine oxidase, citrates, and diet therapy are specified. An attempt was made to generalize the role of disorders of purine metabolism from the positions of not only the urologist, but also of internal medicine as a whole.

uric acid, purine metabolism, gout, urate nephrolithiasis, xanthine oxidase inhibitors, allopurinolum, febuxostat, citrates