Slow acting symptomatic agents in the therapy of osteoarthritis

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Abstract

The article presents the definition of osteoarthritis (OA), the main manifestations of the disease, the problems of OA therapy, the algorithm for managing patients with OA, the importance of educational programs, the combination of pharmacological and non-pharmacological methods of treatment, and the approach to prescribing analgesic therapy. The use of slow-acting symptomatic agents with high safety, symptom-modifying and potential structural-modifying action is discussed. Data on the features of the mechanism of action, clinical efficacy and safety of chondroitin sulfate, glucosamine and their combination are presented. The data of clinical trials of the preparation Arthra® is presented, its effectiveness in relation to pain syndrome and joint function improvement in patients with OA is shown, the safety and tolerability of the drug are noted, as well as its ability to preserve the effect after the end of therapy.

About the authors

E. Yu Pogozheva

V.A.Nasonova Research Institute of Rheumatology

канд. мед. наук, ФГБНУ «НИИ ревматологии им. В.А.Насоновой» 115522, Russian Federation, Moscow, Kashirskoe sh., d. 34a

V. N Amirdzhanova

V.A.Nasonova Research Institute of Rheumatology

Email: lifequality@yandex.ru
д-р мед. наук, ФГБНУ «НИИ ревматологии им. В.А.Насоновой» 115522, Russian Federation, Moscow, Kashirskoe sh., d. 34a

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