Pneumoconiosis in the practice of the attending physician

Cover Page

Cite item

Full Text

Abstract

Pneumoconiosis is an occupational disease of the lungs, which is often found in physician's general practice. Differential diagnosis of various forms of pneumoconiosis is sometimes difficult due to the similarity of their clinical symptoms and X-ray pictures with disseminated processes of different etiology. Pneumoconiosis presented a large group of diseases and classified as fibrotic and non-fibrotic. The most common forms of fibrous types are dust exposure, containing in its composition of silicon dioxide (silicosis, anthracosilicosis, asbestosis), as well as certain types of toxic and allergenic dust -berylliosis actions that can lead to death. The characteristic X-ray and CT signs of fibrotic pneumoconiosis are small reticular nodules scattered along the lymphatic and blood vessels, often with calcification. Magnetic resonance imaging can help the physician in the differential diagnosis of pneumoconiosis and lung cancer. Histological examination is necessary to detect markers of silicosis (silicotic bundle) and asbestosis (asbestos bodies) that serves as the basis for the diagnosis of pneumoconiosis. Identification of interstitial pneumonia and giant cells in heavy metal dust exposure indicates a metalloconiosis. Signs of berylliosis CT are similar to those of sarcoidosis, but the totality of the clinical and pathological features allows us to differentiate these diseases. Timely diagnosis, the decision of expert questions and pathogenetic treatment will help to keep disabled patient.

About the authors

O. S Vasileva

Scientific Research Institute of Pulmonology

Email: ovasil@mail.ru
д-р мед. наук, проф., зав. лаб. экологозависимых и профессиональных легочных заболеваний ФГБУ НИИ пульмонологии 105077, Russian Federation, Moscow, ul. 11-ia Parkovaia, d. 32

N. Yu Kravchenko

Scientific Research Institute of Pulmonology

Email: pulmokongress@mail.ru
науч. сотр. лаб. экологозависимых и профессиональных легочных заболеваний ФГБУ НИИ пульмонологии 105077, Russian Federation, Moscow, ul. 11-ia Parkovaia, d. 32

References

  1. International Labour Organization (ILO), Guidelines for the use of ILO International Classification of Radiographs of Pneumoconiosis. Geneva, Switzerland: ILO, 1980.
  2. Справочник профпатолога. Под ред. Л.Н.Грацианской и В.Е.Ковшило. М.: Медицина, 1977; с. 255-87.
  3. Рашевская А.М., Молоканов К.П., Орлова А.А. Бериллиоз. Клиника, диагностика, лечение, экспертиза трудоспособности. М.: Медицина, 1965; с. 60.
  4. Сенкевич Н.А. Клинические формы силикоза и силикотуберкулеза. Под ред. А.М.Рашевской. М.: Медицина, 1974; с. 200.
  5. Parkers W.R. Occupational lung diseases. London: Butter - worths, 1982; 464-7.
  6. Классификация пневмокониозов. Письмо МЗ и МП РФ от 15.03.1966 г. №11-6/15.
  7. Федеральные клинические рекомендации по диагностике, профилактике и лечению пневмокониозов. Медицина труда и промышленная экология. 2016; 1: 36-48.
  8. Полякова И.Н. Пневмокониозы. В кн.: Респираторная медицина: руководство. Под ред. Г.Чучалина. Т. 2. М.: ГЭОТАР-Медиа, 2007; с. 335-50.
  9. Васильева О.С. Пневмокониозы. РМЖ. 2010; 24: 1441-8.
  10. Шпагина Л.А., Артамонова В.Г., Фишман Б.Б. и соавт. Пневмокониозы. Классификация. Эпидемиология. Патогенез. В кн.: Профессиональные заболевания органов дыхания. Под ред. Н.Ф.Измерова, А.Г.Чучалина. М.: ГЭОТАР-Медиа, 2015; с. 363-488.
  11. Пневмокониозы - симптомы болезни, профилактика, лечение. Eurolab.ua >diseases / 1491.
  12. Akgun M, Araz O, Akkurt I et al. An epidemic of silicosis among former denim sandblasters. Eur Respir J 2008; 32: 1295-303.
  13. De Vuyst P, Camus P. The past and present of pneumoconiosis. Curr Opin Pulm Med 2000; 6: 151-6.
  14. Tjoe Nij E, Burdorf A, Parker J et al. Radiographic abnormalities among construction workers exposed to quartz containing dust. Occup Environ Med 2003; 60: 410-7.
  15. Fujimura N. Pathology and pathophysiology of pneumoconiosis. Curr Opin Pulm Med 2000; 6: 140-4.
  16. Park E.K, Takahashi K, Hoshuyama T et al. Global magnitude of reported and unreported mesothelioma. Environ Health Perspect 2011; 119: 514-8.
  17. Peto J, Decarli A, La Vecchia C et al. The European mesothelioma epidemic. Br J Cancer 1999; 79: 666-72.
  18. Oikonomou A, Muller N.L. Imaging of pneumoconiosis. Imaging 2003; 15: 11-2.
  19. Ross R.M. The clinical diagnosis of asbestosis in this century requires more than a chest radiograph. Chest 2003; 124: 1120-8.
  20. Miller-Quernheim J, Gaede K.E, Fireman E et al. Diagnoses of chronic beryllium disease within cohorts of sarcoidosis patients. Eur Respir J 2006; 27: 1190-5.
  21. Hubbard R, Lewis S, Richards K et al. Occupational exposure to metal or wood dust and aetiology of cryptogenic fibrosingalveolitis. Lancet 1996; 347: 284-9.
  22. Nemery B, Verbeken E.K, Demedts M. Giant cell interstitial pneumonia (hard metal lung disease, cobalt lung). Semin Respir Crit Care Med 2001; 22: 435-48.
  23. Seming C, Kyung S, Myung F et al. Pneumoconiosis: Comparison of Imaging and Pathologic Findings. Education exibit. From the Department of RSNA 2006. http://www.rsna.org/education/rg_cme.html
  24. Doll R, Peto R. The causes of cancer: quantitative estimates of avoidable risks of cancer in the United States today. J Natl Cancer Inst 1981; 66: 1191-308.
  25. Driscoll T, Nelson D.I, Steenland K et al. The global burden of disease due to occupational carcinogens. Am J Ind Med 2005; 48: 419-31.
  26. Van Loon A.J, Kant I.J, Swaen G.M et al. Occupational exposure to carcinogens and risk of lung cancer: results from The Netherlands cohort study. Occup Environ Med 1997; 54: 817-24.
  27. Sood A, Beckett W.S, Cullen M.R. Variable response to long - term corticosteroid therapy in chronic beryllium disease. Chest 2004; 126: 2000-7.

Copyright (c) 2016 Consilium Medicum

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies