Chronic endometritis. Approaches to diagnosis and treatment

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Abstract

Chronical endometritis (CE) is responsible for women infertility. Investigation of histological data of endometrial target biopsy permit to diagnose the CE and elicit activity of inflammation immunohistochemical study of biopsy permit to define more exactly nature of CE, specify local immunological disturbances, distinguish the patients with autoimmune inflammation and local autoimmune answer. Subsets definition of natural killer (NK) cells, B1-, B2-cells, memory B-cells in the peripheral blood, NK, TNK, T-cells cytotoxicity study permit realize monitoring of immune therapy without repeated biopsy realization.Presented data confirm efficiency of Polyoxidonium (azoximer bromide) in therapy of CE and fertility reconstruction.

About the authors

N. M Kalinina

A.M.Nikiforov Russian Center of Emergency and Radiation Medicine

Email: doctkalin@mail.ru
д-р мед. наук, проф., клин. иммунолог, гл. науч. сотр. отд. лабораторной диагностики, проф. каф. терапии и интегративной медицины ИДПО Экстремальная медицина ФГБУ ВЦЭРМ им. А.М.Никифорова МЧС России 194044, Russian Federation, Saint Petersburg, ul. Akademika Lebedeva, d. 4/2

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