Contrast-induced acute kidney injury after computed tomography with contrast media in patients with cardiovascular diseases
- Authors: Vasin A.A.1, Mironova O.I.1, Fomin V.V.1
-
Affiliations:
- Sechenov First Moscow State Medical University (Sechenov University)
- Issue: Vol 23, No 12 (2021)
- Pages: 928-930
- Section: Articles
- URL: https://journals.rcsi.science/2075-1753/article/view/100018
- DOI: https://doi.org/10.26442/20751753.2021.12.201162
- ID: 100018
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Abstract
Aim. To assess the frequency of contrast-induced acute kidney injury (CI-AKI) in patients with cardiovascular diseases (CVD) undergoing computed tomography (CT) with intravenous contrast media.
Materials and methods. In prospective observational study (ClinicalTrials.gov ID NCT04666389) were included 51 patients with CVD undergoing CT with intravenous contrast media administration. The primary endpoint was CI-AKI according to KDIGO criteria [the 25% rise (or 0.5 mg/dl) of serum creatinine from baseline assessed 48–72 hours after administration of contrast media]. There were 51% of women included in the study. The average age was 61.74±1.5. The most frequent cardiovascular disease was hypertension in both men and women – 52 and 39% respectively.
Results. CI-AKI was diagnosed in 2 (3.92%) patients. At the same time, it was not possible to establish statistically significant relationship (p<0.05) between risk factors and the development of CI-AKI.
Conclusion. Cardiovascular diseases may increase the risk of CI-AKI after CT with intravenous contrast media administration. Therefore, it is recommended to evaluate the serum creatinine concentration in such patients.
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##article.viewOnOriginalSite##About the authors
Andrey A. Vasin
Sechenov First Moscow State Medical University (Sechenov University)
Author for correspondence.
Email: vasin_dr@mail.ru
ORCID iD: 0000-0002-6261-3086
Graduate Student
Russian Federation, MoscowOlga Iu. Mironova
Sechenov First Moscow State Medical University (Sechenov University)
Email: mironova_o_yu@staff.sechenov.ru
ORCID iD: 0000-0002-5820-1759
Cand. Sci. (Med.)
Russian Federation, MoscowVictor V. Fomin
Sechenov First Moscow State Medical University (Sechenov University)
Email: vasin_dr@mail.ru
ORCID iD: 0000-0002-2682-4417
D. Sci. (Med.), Prof., Corr. Memb. RAS
Russian Federation, MoscowReferences
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