Preclinical Testing of Domestic Devices Used in out-of-Hospital Circular Arrest
- Authors: Teplov V.M.1, Prasol D.M.1, Romanova E.A.1, Filipenko K.V.2, Kharlamov V.V.3, Raevskiy A.A.4
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Affiliations:
- First St. Petersburg State Medical University named after acad. I.P. Pavlova
- Central Research and Development Institute of Robotics and Technical Cybernetics
- Medical Robotics LLC
- City Ambulance Station
- Issue: No 3 (2024)
- Pages: 61-64
- Section: Experimental Studies
- URL: https://journals.rcsi.science/2070-1004/article/view/358043
- DOI: https://doi.org/10.33266/2070-1004-2024-3-61-64
- ID: 358043
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Full Text
Abstract
Summary. The aim of the study was to evaluate the effectiveness of domestic devices for supporting blood circulation in case of out-of-hospital circulatory arrest during preclinical trials.
Research materials and methods. The study assessed the effectiveness of the Russian cardiac massager “CardioRobot” – an automated device for performing indirect cardiac massage of domestic design. This device has the following technical characteristics: piston type design; compression depth – (50-60±2) mm; compression frequency – (102±2) compressions/min; 2 operating modes – continuous and 30:2; weight – 6.5 kg; continuous battery life – 45 min; trapezoidal compression curve.
To evaluate the device, a comparative experiment was conducted on large mammals (pigs), during which the work of the domestic prototype and the foreign device “LUCAS-2” was compared by comparing the indicators of central hemodynamics and gas exchange.
During the clinical trials of LifeStream ECMO, postmortem extracorporeal membrane oxygenation (ECMO) of two donors was performed. During the experiment, the following were assessed: pO2, pH, pCO2, arterial blood lactate and creatinine concentrations.
Research results and their analysis. During preclinical trials, domestically produced devices demonstrated experimental effectiveness comparable to similar foreign-made products. Currently, the LIFESTREAM ECMO perfusion emergency circulatory restoration complex for human resuscitation has received a certificate and is actively used in the Russian Federation, and the CardioRobot automated chest compression device is undergoing state registration.
About the authors
V. M. Teplov
First St. Petersburg State Medical University named after acad. I.P. Pavlova
Email: vadteplov@mail.ru
Dr. Sc. (Med.); Professor of the Department of Emergency Medicine and Injury Surgery, Head of the Department of Emergency Medicine St. Petersburg
D. M. Prasol
First St. Petersburg State Medical University named after acad. I.P. Pavlova
Email: vadteplov@mail.ru
St. Petersburg
E. A. Romanova
First St. Petersburg State Medical University named after acad. I.P. Pavlova
Email: vadteplov@mail.ru
St. Petersburg
K. V. Filipenko
Central Research and Development Institute of Robotics and Technical Cybernetics
Email: vadteplov@mail.ru
St. Petersburg
V. V. Kharlamov
Medical Robotics LLC
Email: vadteplov@mail.ru
Vsevolozhsk, Leningrad Region
A. A. Raevskiy
City Ambulance Station
Email: vadteplov@mail.ru
St. Petersburg
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