Email this article Ultrasound navigation during retrobulbar blockade in children with retinoblastoma and enucleation of the eyeball
- Authors: Belousova E.I.1, Matinyan N.V.1,2, Tsintsadze A.A.1, Martynov L.A.1, Kuznetsov D.A.1, Kovaleva E.A.1, Ushakova T.L.1,3, Polyakov V.G.1,2,3
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Affiliations:
- Blokhin National Medical Research Center of Oncology
- Pirogov Russian National Research Medical University
- Russian Medical Academy of Continuous Professional Education
- Issue: Vol 15, No 2 (2021)
- Pages: 127-136
- Section: Original articles
- URL: https://journals.rcsi.science/1993-6508/article/view/90096
- DOI: https://doi.org/10.17816/1993-6508-2021-15-2-127-136
- ID: 90096
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Abstract
BACKGROUND: The retrobulbar block in children is used to enucleate analgesia in the intra- and postoperative period and prevent oculocardiac reflex (OCD), postoperative nausea, and vomiting. However, when the block is performed blindly, it results in serious complications.
AIM: This study aimed to evaluate the efficacy and safety of a retrobulbar block performed under ultrasound guidance compared with a retrobulbar block performed blindly during enucleation of the eyeball in children with retinoblastoma.
MATERIALS AND METHODS: A prospective randomized controlled trial was performed. The study included 40 patients who met the inclusion criteria. The patients were divided into two groups: 20 patients who underwent ultrasound-guided retrobulbar blockade (RBВ + ultrasound) and 20 patients who underwent blindly retrobulbar blockade (RBВ).
RESULTS: There was an insignificant decrease in intraoperative opioid requirements in the RBB + ultrasound group, where the average dose of fentanyl was 4±1.4 μg/kg, and in the RBB group, 4.7±0.8 μg/kg (p <0.05).
The time before the administration of the first dose of analgesic in the postoperative period was 4.7±0.8 h in the RBB group and 11.7±3.3 h in the RBB + ultrasound group (p <0.05). VAS and CHIPPS scores obtained 6 h after the end of surgery in the RBB + ultrasound and RBB groups were 1.8 (1.2; 2) and – 2.5 (3.8; 4.5) points (p <0.05), respectively.
CONCLUSION: There was no statistically significant difference between the time of the retrobulbar blockade under ultrasound guidance and the retrobulbar regional block performed blindly. Retrobulbar blockade performed under ultrasound guidance provides a decrease in intraoperative opioid requirements, stable intraoperative hemodynamics, and longer postoperative analgesia.
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##article.viewOnOriginalSite##About the authors
Ekaterina I. Belousova
Blokhin National Medical Research Center of Oncology
Email: e.belousova36@gmail.com
ORCID iD: 0000-0001-9602-3052
Ph.D.
Russian Federation, 23, Kashirskoe sh., Moscow, 115478Nune V. Matinyan
Blokhin National Medical Research Center of Oncology; Pirogov Russian National Research Medical University
Email: n9031990633@yandex.ru
ORCID iD: 0000-0001-7805-5616
SPIN-code: 9829-6657
DSc
Russian Federation, 24, Kashirskoe sh., Moscow, 115478; MoscowAnastasia A. Tsintsadze
Blokhin National Medical Research Center of Oncology
Email: anestesia228@mail.ru
ORCID iD: 0000-0003-1897-0331
Ph.D.
Russian Federation, 23, Kashirskoe sh., Moscow, 115478Leonid A. Martynov
Blokhin National Medical Research Center of Oncology
Email: leonid.martynov@gmail.com
ORCID iD: 0000-0001-9013-2370
SPIN-code: 5278-1343
Russian Federation, 23, Kashirskoe sh., Moscow, 115478
Dmitry A. Kuznetsov
Blokhin National Medical Research Center of Oncology
Email: cbric89@mail.ru
ORCID iD: 0000-0003-3569-5255
SPIN-code: 3140-2275
Russian Federation, 23, Kashirskoe sh., Moscow, 115478
Ekaterina A. Kovaleva
Blokhin National Medical Research Center of Oncology
Author for correspondence.
Email: Mel_amory@mail.ru
ORCID iD: 0000-0001-9492-034X
Russian Federation, 23, Kashirskoe sh., Moscow, 115478
Tatyana L. Ushakova
Blokhin National Medical Research Center of Oncology; Russian Medical Academy of Continuous Professional Education
Email: ushtat07@mail.ru
ORCID iD: 0000-0003-3263-6655
SPIN-code: 2065-8779
DSc
Russian Federation, 24, Kashirskoe sh., Moscow, 115478; MoscowVladimir G. Polyakov
Blokhin National Medical Research Center of Oncology; Pirogov Russian National Research Medical University; Russian Medical Academy of Continuous Professional Education
Email: vgp-04@mail.ru
ORCID iD: 0000-0002-8096-0874
SPIN-code: 8606-3120
DSc, Professor
Russian Federation, 23, Kashirskoe sh., Moscow, 115478; Moscow; MoscowReferences
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