DEXAMETHASONE AND POSTOPERATIVE ANALGESIA


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Abstract

The review contains the analysis of analgesic and opioid-saving action of dexamethasone in its systemic administration. These effects are most evident in the preventive administration of the drug 1.5-2 hours before surgery. The most promising area of application of dexamethasone as a component of anesthetic support is laparoscopic surgery. In the orthopedic clinic, the use of dexamethasone can increase the duration of action of peripheral nerve blockades and plexuses (both sensory and motor block), while perineural administration (addition to the local anesthetics) has no advantages over intravenous injection. Single administration of a standard dose of dexamethasone (8 mg) is not accompanied by the occurrence of clinically significant side effects.

About the authors

Alexei M. Ovechkin

I.M.Sechenov First Moscow State Medical University

Email: ovechkin_alexei@mail.ru
MD, PhD, DSc, professor, Department of Anesthesiology and Reanimatology, I.M.Sechenov First Moscow State Medical University, Moscow, 119991, Russian Federation Moscow, 119991, Russian Federation

M. E Politov

I.M.Sechenov First Moscow State Medical University

Moscow, 119991, Russian Federation

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