EPIDURAL MORPHINE IN PEDIATRIC ONCOLOGIC SURGERY


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Abstract

Epidural administration of opioids effectively prevents the sensitization of nociceptive neurons of the posterior horn of the spinal cord, induced by surgical trauma, without the development of motor and autonomic blockade. Study includes 52 patients aged 1 month to 18 years with malignant tumors who underwent surgical treatment at the Pediatric Oncology and Hematology Research Institute, during 2009-2016 years. Surgeries were combined (thoraco-laparotomy). The method of epidural use of morphine in pediatric oncosurgery is presented.

About the authors

Nune V. Matinyan

Blokhin Russian Cancer Research Center (RCRC) of the Ministry of Health of Russia, Pediatric Oncology and Hematology Research Institute; Pediatric anesthesiology and intensive care department, Pirogov Russian National Research Medical University

Email: n9031990633@ya.ru
MD, PhD, DSc, prof., Blokhin Russian Cancer Research Center (RCRC) of the Ministry of Health of Russia, Pediatric Oncology and Hematology Research Institute, 115478, Moscow; Pediatric anesthesiology and intensive care department, Pirogov Russian National Research Medical University, 117997, Moscow, Russian Federation 115478, Moscow; 117997, Moscow

I. A Letyagin

Blokhin Russian Cancer Research Center (RCRC) of the Ministry of Health of Russia, Pediatric Oncology and Hematology Research Institute

115478, Moscow

L. A Martynov

Blokhin Russian Cancer Research Center (RCRC) of the Ministry of Health of Russia, Pediatric Oncology and Hematology Research Institute

115478, Moscow

A. V Sotnikov

Blokhin Russian Cancer Research Center (RCRC) of the Ministry of Health of Russia, Pediatric Oncology and Hematology Research Institute

115478, Moscow

A. P Kazantsev

Blokhin Russian Cancer Research Center (RCRC) of the Ministry of Health of Russia, Pediatric Oncology and Hematology Research Institute

115478, Moscow

D. V Rybakova

Blokhin Russian Cancer Research Center (RCRC) of the Ministry of Health of Russia, Pediatric Oncology and Hematology Research Institute

115478, Moscow

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