Email this article Postoperative analgesia with the use of nefopam and ketoprofen in cardiosurgical patients
- Authors: Eremenko A.A1, Sorokina L.S1
-
Affiliations:
- FSBI “Boris Petrovsky National Research Center for Surgery" RAMS
- Issue: Vol 8, No 3 (2014)
- Pages: 26-32
- Section: Articles
- URL: https://journals.rcsi.science/1993-6508/article/view/36224
- DOI: https://doi.org/10.17816/ра.v8i3.36224
- ID: 36224
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Abstract
The study was conducted in order to test effectiveness and safety of different schemes of postoperative analgesia in 135 patient undergone myocardium revascularization surgery and acquired heart defect corrections. Six combinations of postoperative analgesia were studied. The effectiveness and safety were approved for all of 6 postoperative analgesia schemes in cardiosurgical patients. The frequency of nausea, vomiting, dizziness and weakness was significantly higher in the group of PCA with Trimeperidine as monotherapy than in other groups. Combination of Nefopam and Ketoprofen provided the most expressed analgesic effect. Administration of Nefopam and Ketoprofen before extubation reduced the intensity of pain (in average for 50%) and promoted the early stirring up of patients. Combined administration of Nefopam and Ketoprofen provided opioid-saving effect for 79%, while 55% of patients don't need additional opioid analgesic administration.
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##article.viewOnOriginalSite##About the authors
A. A Eremenko
FSBI “Boris Petrovsky National Research Center for Surgery" RAMS119991, Moscow
L. S Sorokina
FSBI “Boris Petrovsky National Research Center for Surgery" RAMS119991, Moscow
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