Email this article The Role of Regional Anesthesia in the Development of Surgical Stress Response during Major Spine Surgery
- Authors: Ezhevskaya A.A1, Ovechkin A.M2
-
Affiliations:
- FSBI “Scientific and Research Institute of Traumatology and Orthopedics”, Nizhniy Novgorod
- FSBI “Sechenov First Moscow State Medical University”
- Issue: Vol 7, No 4 (2013)
- Pages: 25-29
- Section: Articles
- URL: https://journals.rcsi.science/1993-6508/article/view/36199
- DOI: https://doi.org/10.17816/ра.v7i4.36199
- ID: 36199
Cite item
Full Text
Abstract
Objective: optimization of regional anesthesia for major spine surgery and the evaluation of its effects on the endocrine-metabolic and inflammatory stress response. This study included 205 patients. Two groups of patients were randomly allocated: Group 1 used thoracic epidural analgesia and general anesthesia, and Group 2 had general anesthesia. The study has shown that epidural analgesia provided better pain relief, less blood loss during and after surgery in spinal deformity surgery. The use of epidural analgesia provided better pain control, less bleeding, and a lower surgical stress response than general anesthesia during major spine surgery.
Full Text
##article.viewOnOriginalSite##About the authors
A. A Ezhevskaya
FSBI “Scientific and Research Institute of Traumatology and Orthopedics”, Nizhniy Novgorod
A. M Ovechkin
FSBI “Sechenov First Moscow State Medical University”
References
- Howard S.A. Principles and Techniques of Spine Surgery. Williams & Wilkins. 1994; 129-155.
- Соленкова А.В., Лубнин А.Ю., Арестов О.Г., Шевелев И.Н. Эффективность и безопасность эпидуральной анестезии при операциях на позвоночнике. Регионарная анестезия и лечение боли. Тематический сборник. 2004; 229-238.
- Raw D.A., Beattie J.K., Hunter J.M. Anaesthesia for spinal surgery in adults. Br. J. Anaesth. 2003; 91: 886-904.
- Starkweather A.R., Witek-Janusek L., Nockels R.P. et al. Immune function, pain, and psychological stress in patients undergoing spinal surgery. Spine. 2006. Aug 15; 31(18): E641-647.
- Соленкова А.В., Лубнин А.Ю., Шевелев И.Н. Возможности применения эпидуральной анальгезии в послеоперационном периоде при оперативных вмешательствах на позвоночнике и спинном мозге. Регионарная анестезия и лечение острой боли. 2008; 4 (II): 53-63.
- Соленкова А.В., Лубнин А.Ю., Тенедиева В.Д. и др. Эпидуральная анестезия при оперативных вмешательствах на позвоночнике и спинном мозге. Часть I. Сравнительный анализ адекватности анестезиологической защиты в условиях эпидуральной анестезии и нейролептанальгезии. Анестезиология и реаниматология. 2000; (4).
- Greenberg P.E., Brown M.D. Epidural anesthesia for lumbar spine surgery. J. Spin. Disord. 1988; 1: 139-143.
- Gottschalk A., Freitag M., Tank S., Burmeister M. et al. Quality of postoperative pain using an intraoperatively placed epidural catheter after major lumbar spinal surgery. Anesthesiology. 2004; 101: 175-180.
- Hollmann M.W., Strumper D., Durieux M.E. The poor man's epidural: systemic local anesthetics for improving postoperative outcomes. Med Hypotheses. 2004; 63: 386-389.
- Marz P., Cheng J.G., Gadient R.A., et al. Sympathetic neurons can produce and respond to interleukin 6. Proc Natl Acad Sci U S A. 1998; 95: 3251-3256.
- Volk T., Schenk M., Voigt K., et al. Postoperative epidural anesthesia preserves lymphocyte, but not monocyte, immune function after major spine surgery. Anesth Analg. 2004; 98: 1086-1092.
