Infusion of esmolol and thoracic epidural anesthesia as methods of intraoperational control of cardiac risk


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Abstract

The study was performed to compare thoracic epidural anaesthesia and esmolol infusion capability to provide optimal hemodynamic conditions for myocardial functioning. The study included 45 patients with increased cardiac risk undergoing opened abdominal surgery. The patients were randomized to receive either intravenous anaesthesia or combined (intravenous + thoracic epidural) anaesthesia or intravenous anaesthesia with esmolol infusion. The study results demonstrate that thoracic epidural anaesthesia and esmolol infusion provide effective control of hemodynamic response to trachea intubation and prevent tachycardia during the procedure. B-type natriuretic peptide level decreased during surgery while using two pointed techniques in contrast to the intravenous anaesthesia alone. This fact indicates comfortable conditions for myocardial functioning and proves that these techniques are cardioprotective.

About the authors

O. A Shayda

State Institution “Dnepropetrovsk Medical Academy”

Yu. Yu Kobelyatskiy

State Institution “Dnepropetrovsk Medical Academy”

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