Ibuprofen for intravenous administration: new possibilities for the use of NSAIDs in postoperative pain management

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Abstract

Non-steroidal anti-inflammatory drugs are an essential component of postoperative multimodal analgesia. Their analgesic efficacy has been confirmed by data from evidence-based medicine. The appearance of an intravenous form of ibuprofen on the Russian pharmaceutical market expands the possibilities of using NSAIDs in postoperative pain managment schemes. Ibuprofen characterized a high analgesic potential and an optimal safety profile in relation to the risk of gastrointestinal and cardiovascular complications.

About the authors

Аlexei M. Ovechkin

Sechenov First Moscow State Medical University

Author for correspondence.
Email: ovechkin_alexei@mail.ru
ORCID iD: 0000-0002-3453-8699
SPIN-code: 1277-9220

MD, Dr. Sci. (Med.), professor

Russian Federation, Moscow

Mikhail E. Politov

Sechenov First Moscow State Medical University

Email: ovechkin_alexei@mail.ru
ORCID iD: 0000-0003-0623-4927
SPIN-code: 2048-9705

MD, Cand. Sci. (Med.), associate professor

Russian Federation, Moscow

Sergey V. Sokologorskiy

Sechenov First Moscow State Medical University

Email: ovechkin_alexei@mail.ru
ORCID iD: 0000-0001-6805-9744
SPIN-code: 8933-8819

MD, Dr. Sci. (Med.), professor

Russian Federation, Moscow

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Supplementary files

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2. Fig. Classification of NSAIDs according to the degree of selectivity for COX-1 and COX-2 [22].

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Copyright (c) 2022 Ovechkin А.M., Politov M.E., Sokologorskiy S.V.

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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
 


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