Antenatal risk factors for retinopathy of premature
- 作者: Makogon S.1,2, Gorbacheva N.1,2, Khlopkova Y.2
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隶属关系:
- Altai Regional Ophthalmological Hospital
- Altai State Medical University
- 期: 卷 17, 编号 4 (2022)
- 页面: 49-59
- 栏目: Reviews
- URL: https://journals.rcsi.science/1993-1859/article/view/232331
- DOI: https://doi.org/10.17816/rpoj109227
- ID: 232331
如何引用文章
详细
This literature review presents the antenatal risk factors for the development of retinopathy of prematurity (ROP). Despite advances in antenatal and neonatal therapeutic interventions, screening, and follow-up, ROP remains a potentially vision-threatening retinopathy that requires careful monitoring and timely intervention to prevent the progression of adverse visual impairment or blindness. ROP is a multifactorial disease. The main risk factors are low gestational age and low birth weight. Recent experimental and clinical data support the hypothesis that multiple antenatal factors are involved in the etiology and progression of ROP. These factors include the age of the mother, maternal diseases, pregnancy-associated maternal pathologies, use of drugs to correct these conditions, and inflammatory process. Their roles are ambiguous and often contradictory. The physiology of the mother and placenta can significantly influence the risk of ROP development in preterm infants. The placenta connects the mother’s body and the fetus, and it functions in the exchange of nutrients and oxygen between the mother and the fetus. Therefore, any pathological changes in the mother’s body entail changes in the placenta, which this directly affects the fetus. A sudden loss of placental support is detrimental to the development of infants in the immediate postnatal period. Thus, these factors should be taken into account when assessing the risk of ROP development to predict and prevent poor vision in children.
作者简介
Svetlana Makogon
Altai Regional Ophthalmological Hospital; Altai State Medical University
编辑信件的主要联系方式.
Email: vvk_msi@mail.ru
ORCID iD: 0000-0002-3943-1188
SPIN 代码: 4809-7546
MD, Dr. Sci. (Med.)
俄罗斯联邦, Barnaul; BarnaulNatalya Gorbacheva
Altai Regional Ophthalmological Hospital; Altai State Medical University
Email: vvk_msi@mail.ru
ORCID iD: 0000-0002-5586-9796
MD, ophthalmologist
俄罗斯联邦, Barnaul; BarnaulYulia Khlopkova
Altai State Medical University
Email: vvk_msi@mail.ru
ORCID iD: 0000-0002-7615-2057
MD, ophthalmologist
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