LEVOFLOXACIN IN THERAPY OF BACTERIAL INFECTIONS IN CHILDREN
- Authors: Sidorenko EI1, Markova EY.1, Matveyev AV1, Zakharchenko AV2
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Affiliations:
- РГМУ, Москва
- Морозовская детская клиническая больница
- Issue: Vol 5, No 1 (2010)
- Pages: 34-36
- Section: Articles
- URL: https://journals.rcsi.science/1993-1859/article/view/37540
- DOI: https://doi.org/10.17816/rpoj37540
- ID: 37540
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Abstract
The assessment of clinical efficiency of local application of Levofloxacin 0.5% in eye drops in treatment of inflammatory diseases in children was performed and cytotoxicity of the medication was studied. The authors examined 34 children (62 eyes) with various inflammatory diseases of the organ of vision. It was shown that the terms of complete regression of the disease symptoms were observed at the period from 5-6 to 18-19 days depending on the nosologic form. Taking into account a wide spectrum of drug action and clinical efficiency of Levofloxacin, the absence of clinically pronounced effects and low keratotoxicity of the medication, instillation form of Levofloxacin 0.5% (Oftaquix(r), Santen) can be recommended for wide application as empiric therapy in children at the age of the 1st year of life with inflammatory eye diseases.
About the authors
E I Sidorenko
РГМУ, Москвад-р мед. наук, проф. член-корр. РАМН; РГМУ, Москва
E Yu Markova
РГМУ, Москвад-р мед. наук; РГМУ, Москва
A V Matveyev
РГМУ, Москвааспирант; РГМУ, Москва
A V Zakharchenko
Морозовская детская клиническая больницаМорозовская детская клиническая больница
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