电邮这篇文章 Study design and immediate results of combined opto-pharmacological treatment of progressive myopia in children
- 作者: Tarutta E.P.1, Proskurina O.V.1, Tarasova N.A.1, Arutyunyan S.G.1, Markosyan G.A.1, Milash S.V.1
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隶属关系:
- Helmholtz National Medical Research Center of Eye Diseases
- 期: 卷 18, 编号 3 (2023)
- 页面: 155-161
- 栏目: Original study article
- URL: https://journals.rcsi.science/1993-1859/article/view/163807
- DOI: https://doi.org/10.17816/rpoj516533
- ID: 163807
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详细
Eye drops that affect dynamic refraction and pupil width can enhance the effect of optical treatment by forming relative peripheral myopic defocus on the refractogenesis of children with myopia.
AIM: To evaluate the effect of combined optopharmacological effects on the dynamics of central and peripheral refraction, accommodation, visual function, and choroid thickness in children with progressive myopia.
MATERIAL AND METHODS: The study involved 40 children aged 8–13 years with myopia from 1.75 to 6.37 dptr. These children were given glasses forming peripheral myopic defocus for the first time. Of these, 20 children, after 1 month, were prescribed combined eye drops containing 0.8% tropicamide and 5% phenylephrine.
RESULTS: One month from the start of wearing glasses, the monocular visual acuity with glasses was 0.94±0.02. After the eye drop application, the visual acuity with glasses significantly increased to 1.06±0.02 (p <0.01). This was explained by a significant decrease in the usual tone of open-field accommodation (PTA-OP) to +0.01±0.04. A clinically significant (p <0.05) increase in relative accommodation reserves (ZOA) by 0.71 dptr was revealed, and opto-pharmacological effects were not observed on mesopic contrast sensitivity and peripheral refraction. Choroid thickness increased by 4.7%.
CONCLUSION: During the observation period, accommodation tended to normalize, and the thickness of the choroid increased clinically significantly. Further observations are needed to evaluate the effectiveness of combined optopharmacological treatment in comparison with optical exposure.
作者简介
Elena Tarutta
Helmholtz National Medical Research Center of Eye Diseases
Email: elenatarutta@mail.ru
ORCID iD: 0000-0002-8864-4518
MD, Dr. Sci. (Med.), Рrofessor
俄罗斯联邦, MoscowOlga Proskurina
Helmholtz National Medical Research Center of Eye Diseases
编辑信件的主要联系方式.
Email: proskourina@mail.ru
ORCID iD: 0000-0002-2496-2533
SPIN 代码: 1057-5866
MD, Dr. Sci. (Med.)
俄罗斯联邦, MoscowNatalia Tarasova
Helmholtz National Medical Research Center of Eye Diseases
Email: tar221@yandex.ru
ORCID iD: 0000-0002-3164-4306
SPIN 代码: 3056-4316
MD, Cand. Sci. (Med.)
俄罗斯联邦, MoscowSona Arutyunyan
Helmholtz National Medical Research Center of Eye Diseases
Email: arutyunyansg@mail.ru
ORCID iD: 0000-0002-3788-2073
MD, Cand. Sci. (Med.)
俄罗斯联邦, MoscowGajane Markosyan
Helmholtz National Medical Research Center of Eye Diseases
Email: dvdomdv@mail.ru
ORCID iD: 0000-0002-2841-6396
MD, Dr. Sci. (Med.)
俄罗斯联邦, MoscowSergey Milash
Helmholtz National Medical Research Center of Eye Diseases
Email: sergey_milash@yahoo.com
ORCID iD: 0000-0002-3553-9896
SPIN 代码: 5224-4319
MD, Cand. Sci. (Med.)
俄罗斯联邦, Moscow参考
- Tarutta EP, Proskurina OV, Milash SV, et al. Peripheral defocus induced by «Perifocal-m» spectacles and myopia progression in children. Russian Pediatric Ophthalmology. 2015;10(2):33–37. (In Russ).
- Tarutta EP, Proskurina OV, Tarasova NA, et al. Long-term results of perifocal defocus spectacle lens correction in children with progressive myopia. The Russian Annals of Ophthalmology. 2019;135(5):46–53. (In Russ). doi: 10.17116/oftalma201913505146
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- Proskurina OV, Golubev SYu, Markova EYu. Sub”ektivnye metody issledovaniya akkomodatsii. In: Katargina LA, editor. Akkomodatsiya. Rukovodstvo dlya vrachei. Moscow: Aprel’; 2012. P. 40–49. (In Russ).
- Tarutta EP, Proskurina OV, Tarasova NA, et al. Kachestvo zreniya i adaptatsiya k ochkam s novymi linzami dlya kontrolya miopii Stellest. 14th Russian National Ophthalmological Forum. 2021;1:317–319. (In Russ).
- Proskurina OV, Tarasova NA, Markosyan GA, et al. Аdaptation and quality of vision in glasses with lenses for the control of stellest myopia with built-in high-spherical microlenses. Russian Pediatric Ophthalmology. 2022;17(2):5–12. (In Russ). doi: 10.17816/rpoj97296
- Chen Z, Xue F, Zhou J, et al. Effects of оrthokeratology on сhoroidal thickness and axial length. Optom Vis Sci. 2016;93(9):1064–1071. doi: 10.1097/OPX.0000000000000894
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