Effect of solvent type and concentration on size and morphology of arbidol microparticles obtained by supercritical antisolvent precipitation
- Autores: Vorobei A.M.1,2, Pokrovskiy O.I.1, Ustinovich K.B.1, Krotova L.I.3, Parenago O.O.1,2, Lunin V.V.1,2
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Afiliações:
- Kurnakov Institute of General and Inorganic Chemistry
- Department of Chemistry
- Institute of Laser and Information Technologies
- Edição: Volume 10, Nº 7 (2016)
- Páginas: 1072-1077
- Seção: Article
- URL: https://journals.rcsi.science/1990-7931/article/view/198467
- DOI: https://doi.org/10.1134/S1990793116070198
- ID: 198467
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Resumo
The capability of arbidol microparticle preparation by supercritical antisolvent (SAS) precipitation was demonstrated. A nonmonotonic dependence of the average particle size on the concentration was found, while the position of the minimum is dependent on the type of solvent used. It is possible to prepare Arbidol particles of various morphology and size from several microns to several hundred microns depending on the conditions.
Sobre autores
A. Vorobei
Kurnakov Institute of General and Inorganic Chemistry; Department of Chemistry
Autor responsável pela correspondência
Email: vorobei@supercritical.ru
Rússia, Moscow; Moscow
O. Pokrovskiy
Kurnakov Institute of General and Inorganic Chemistry
Email: vorobei@supercritical.ru
Rússia, Moscow
K. Ustinovich
Kurnakov Institute of General and Inorganic Chemistry
Email: vorobei@supercritical.ru
Rússia, Moscow
L. Krotova
Institute of Laser and Information Technologies
Email: vorobei@supercritical.ru
Rússia, Moscow
O. Parenago
Kurnakov Institute of General and Inorganic Chemistry; Department of Chemistry
Email: vorobei@supercritical.ru
Rússia, Moscow; Moscow
V. Lunin
Kurnakov Institute of General and Inorganic Chemistry; Department of Chemistry
Email: vorobei@supercritical.ru
Rússia, Moscow; Moscow
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