The effect of vitamin C on the ratio of collagen types I and III in the periprosthesis area in mice
- Authors: Ivanov S.V.1, Ivanov I.S.1, Tsukanov A.V.1, Gafarov G.N.1, Obyedkov E.G.1
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Affiliations:
- Kursk State Medical University
- Issue: Vol 10, No 6 (2016)
- Pages: 453-457
- Section: Article
- URL: https://journals.rcsi.science/1990-519X/article/view/212209
- DOI: https://doi.org/10.1134/S1990519X16060031
- ID: 212209
Cite item
Abstract
The aim of this study was to examine the collagen-stimulating effect of ascorbic acid on the growth of the Parieten ProGrip implanted synthetic hernia prosthesis. The characteristics of collagenogenesis in the anterior abdominal wall were assayed with polarized microscopy. We suggest a new way to stimulate a reparation process with ascorbic acid that will help to optimize forming functionally matured structures of connective tissue of the anterior abdominal wall surrounding endoprosthesis. The results of our investigation show that vitamin C has a positive effect on the collagen synthesis in the periprosthetic capsule for any type of endoprosthesis. This was proven by the statistically significant increase in the ratio of collagen I and III types with vitamin C to the animal diet.
About the authors
S. V. Ivanov
Kursk State Medical University
Author for correspondence.
Email: ivanov.is@mail.ru
Russian Federation, Kursk, 305004
I. S. Ivanov
Kursk State Medical University
Email: ivanov.is@mail.ru
Russian Federation, Kursk, 305004
A. V. Tsukanov
Kursk State Medical University
Email: ivanov.is@mail.ru
Russian Federation, Kursk, 305004
G. N. Gafarov
Kursk State Medical University
Email: ivanov.is@mail.ru
Russian Federation, Kursk, 305004
E. G. Obyedkov
Kursk State Medical University
Email: ivanov.is@mail.ru
Russian Federation, Kursk, 305004