The effect of vitamin C on the ratio of collagen types I and III in the periprosthesis area in mice
- Авторы: Ivanov S.1, Ivanov I.1, Tsukanov A.1, Gafarov G.1, Obyedkov E.1
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Учреждения:
- Kursk State Medical University
- Выпуск: Том 10, № 6 (2016)
- Страницы: 453-457
- Раздел: Article
- URL: https://journals.rcsi.science/1990-519X/article/view/212209
- DOI: https://doi.org/10.1134/S1990519X16060031
- ID: 212209
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Аннотация
The aim of this study was to examine the collagen-stimulating effect of ascorbic acid on the growth of the Parieten ProGrip implanted synthetic hernia prosthesis. The characteristics of collagenogenesis in the anterior abdominal wall were assayed with polarized microscopy. We suggest a new way to stimulate a reparation process with ascorbic acid that will help to optimize forming functionally matured structures of connective tissue of the anterior abdominal wall surrounding endoprosthesis. The results of our investigation show that vitamin C has a positive effect on the collagen synthesis in the periprosthetic capsule for any type of endoprosthesis. This was proven by the statistically significant increase in the ratio of collagen I and III types with vitamin C to the animal diet.
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S. Ivanov
Kursk State Medical University
Автор, ответственный за переписку.
Email: ivanov.is@mail.ru
Россия, Kursk, 305004
I. Ivanov
Kursk State Medical University
Email: ivanov.is@mail.ru
Россия, Kursk, 305004
A. Tsukanov
Kursk State Medical University
Email: ivanov.is@mail.ru
Россия, Kursk, 305004
G. Gafarov
Kursk State Medical University
Email: ivanov.is@mail.ru
Россия, Kursk, 305004
E. Obyedkov
Kursk State Medical University
Email: ivanov.is@mail.ru
Россия, Kursk, 305004