Ectopic adrenocortical adenoma in the renal sinus: A clinical case
- 作者: Trushkin R.N.1,2, Ognerubov N.A.3, Sokolov S.A.2, Dolgov S.A.2, Shcheglov N.E.2, Sokolov A.A.4, Urusova L.S.5, Pachuashvili N.V.5
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隶属关系:
- Peoples' Friendship University of Russia named after Patrice Lumumba
- City Clinical Hospital №52
- Russian Medical Academy of Continuous Professional Education
- Central Clinical Hospital with Polyclinic
- Endocrinology Research Centre
- 期: 卷 27, 编号 1 (2025)
- 页面: 42-45
- 栏目: Articles
- URL: https://journals.rcsi.science/1815-1434/article/view/291147
- DOI: https://doi.org/10.26442/18151434.2025.1.203201
- ID: 291147
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Background. Adrenal ectopy is a congenital anomaly of the endocrine system. It occurs in less than 1% of the adult population. Ectopy lesions consist mainly of cortex and a minimal amount of medulla. Ectopic adenomas of the adrenal cortex are small, non-functional, asymptomatic, and usually found incidentally. They are found in the kidney only in 0.1–0.6% of observations.
Aim. To present a rare case of non-functioning ectopic adrenocortical adenoma in the renal sinus.
Results. A 56-year-old man underwent a routine medical examination, and an ultrasound showed a tumor in the renal sinus. According to X-ray computerized and contrast-enhanced magnetic resonance imaging (MRI), a soft tissue vascularized mass in the renal sinus on the right was found, 29×15×20 mm in size. The density on the Hounsfield scale was +15HU with heterogeneous contrast uptake (up to +75HU), and the mass was closely adjacent to the renal artery and vein. No abnormalities were detected in the adrenal glands. According to MRI, the tumor had a heterogeneous structure with a signal reduction in T2 mode with diffusion restriction. Morphological verification was impossible due to anatomical features. A nephrectomy was performed for suspected renal cell carcinoma of the renal hilum. In pathohistological examination, the tumor was represented by light and eosinophilic cells; immunohistochemistry revealed a pronounced expression of SF1, Melan A, and CYP11B2 biomarkers. Ectopic cortical adrenal adenoma in the renal sinus was diagnosed. The patient was examined in 3 months, and no recurrence or functional activity was detected.
Conclusion. Ectopic adrenocortical adenoma in the renal sinus is extremely rare and usually non-functional. X-ray computed tomography and MRI are sensitive methods for localizing ectopic adrenal tumors. The density value of the mass in the native mode of 10–20 HU indicates a high intracellular lipid content. A surgical method is recommended for the treatment of functional and non-functional adenomas. The final diagnosis is established by histological and immunohistochemical examinations.
作者简介
Ruslan Trushkin
Peoples' Friendship University of Russia named after Patrice Lumumba; City Clinical Hospital №52
Email: ognerubov_n.a@mail.ru
ORCID iD: 0000-0002-3108-0539
D. Sci. (Med.)
俄罗斯联邦, Moscow; MoscowNikolai Ognerubov
Russian Medical Academy of Continuous Professional Education
编辑信件的主要联系方式.
Email: ognerubov_n.a@mail.ru
ORCID iD: 0000-0003-4045-1247
D. Sci. (Med.), D. Sci. (Law), Prof.
俄罗斯联邦, MoscowSergey Sokolov
City Clinical Hospital №52
Email: ognerubov_n.a@mail.ru
ORCID iD: 0009-0004-7016-2360
SPIN 代码: 5232-7116
Urologist
俄罗斯联邦, MoscowSergey Dolgov
City Clinical Hospital №52
Email: ognerubov_n.a@mail.ru
ORCID iD: 0009-0008-6537-1327
Clinical Resident
俄罗斯联邦, MoscowNikolai Shcheglov
City Clinical Hospital №52
Email: ognerubov_n.a@mail.ru
ORCID iD: 0000-0002-1018-8460
Cand. Sci. (Med.)
俄罗斯联邦, MoscowAleksandr Sokolov
Central Clinical Hospital with Polyclinic
Email: ognerubov_n.a@mail.ru
ORCID iD: 0009-0007-0302-0428
SPIN 代码: 5887-1880
Cand. Sci. (Med.)
俄罗斯联邦, MoscowLiliya Urusova
Endocrinology Research Centre
Email: ognerubov_n.a@mail.ru
ORCID iD: 0000-0001-6891-0009
D. Sci. (Med.)
俄罗斯联邦, MoscowNano Pachuashvili
Endocrinology Research Centre
Email: ognerubov_n.a@mail.ru
ORCID iD: 0000-0002-8136-0117
Cand. Sci. (Med.)
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