Clinical effectiveness of comprehensive evaluation of soft tissue inflammation during preparation and treatment by dental implantation: A case report
- Authors: Gus’kov A.V.1, Nikiforov A.A.1, Oleynikov A.A.1, Gadzhiev A.B.1
-
Affiliations:
- Ryazan State Medical University
- Issue: Vol 27, No 3 (2023)
- Pages: 171-181
- Section: Clinical Investigation
- URL: https://journals.rcsi.science/1728-2802/article/view/131231
- DOI: https://doi.org/10.17816/dent393749
- ID: 131231
Cite item
Abstract
At the Department of Orthopedic Dentistry and Orthodontics of the Ryazan State Medical University, one patient (A.) underwent after tooth extraction at the orthopedic rehabilitation using immediate prosthetics, and another patient (B.) was cured after extraction proceeded naturally. Both patients underwent dental implantation 4 months later. After tooth extraction and implantation, both patients underwent complex diagnostic observations on days 7, 20, and 30 through objective, instrumental, and laboratory follow-up of inflammation using the Schiller–Pisarev test, laser Doppler flowmetry (LDF), and assessment of the level of pro-inflammatory cytokines interleukin 6 (IL-6) and tumor necrosis factor (TNF-α) and C-reactive protein (CRP). After tooth extraction on day 30, the clinical picture of both patients indicated complete subsidence of inflammation and stabilization of repair. The IL, CRP, and TNF-α levels were 1.36 and B. 1.75 pg/mL, 0.68 and 0.88 mg/L, and 17.8 and 21.3 pg/mL in patients A and B, respectively. LDF indicators were 18.47 conventional units in patient A, and the microcirculation parameter was 11.46 conventional units in patient B. Thirty days after implantation, the levels of IL-6, CRP, and TNF-α were 1.39 and 1.78 pg/mL, 0.74 and 0.92 mg/mL, and 18.9 and 20.2 pg/mL, respectively. The LDF values were 20.35 units in patient A, and the microcirculation parameter was 19.62 units in patient B. Comprehensive analysis of inflammation is necessary because of its high information content and ability to identify possible complications.
Full Text
##article.viewOnOriginalSite##About the authors
Alexander V. Gus’kov
Ryazan State Medical University
Email: guskov74@gmail.com
ORCID iD: 0000-0001-9612-0784
SPIN-code: 3758-6378
MD, Cand. Sci. (Med.), Assistant Professor
Russian Federation, RyazanAleksandr A. Nikiforov
Ryazan State Medical University
Email: alnik003@yandex.ru
ORCID iD: 0000-0001-9742-4528
SPIN-code: 8366-5282
MD, Cand. Sci. (Med.), Assistant Professor
Russian Federation, RyazanAleksandr A. Oleynikov
Ryazan State Medical University
Email: bandprod@yandex.ru
ORCID iD: 0000-0002-2245-1051
SPIN-code: 5579-5202
Assistant Lecturer
Russian Federation, RyazanAzim B. Gadzhiev
Ryazan State Medical University
Author for correspondence.
Email: 101azim@mail.ru
ORCID iD: 0009-0003-0334-8432
SPIN-code: 5807-3491
Student
Russian Federation, RyazanReferences
- Gvetadze RSh, Arzhantsev AP, Perfil’ev SA, Sharova EV. Clinical and radiological aspects of immediate dentures for the preparation of prosthetic bed before dental implantation. Russian Journal of Dentistry. 2013;(6):15–20. (In Russ).
- Kulakov AA., Abramyan SV, Arzhantsev AP. Dental’naya implantatsiya. Natsional’noe rukovodstvo. 2nd ed. Kulakov AA, editor. Moscow: GEOTAR-Media; 2022. (In Russ).
- Durnovo EA, Chekareva II, Grekhov AV, et al. Trust-based relationship between patient and doctor as guaranty of successful management of dental implantation complications. Science of the Young (Eruditio Juvenium). 2022;10(1):91–100. (In Russ). doi: 10.23888/HMJ202210191-100
- Shuturminskiy VH, Labunets VA, Kirichek AV. Influence of direct prostheses on the condition of the alveolar processes during dental implantation. Saudi Dent J. 2022;34(1):51–55. doi: 10.1016/j.sdentj.2021.10.002
- Ganzha IR, Akhmadieva EO. The new algorithm of soft tissue wounds management depending on the type of healing. The Journal of scientific articles Health and Education millennium. 2018;20(12):65–69. (In Russ). doi: 10.26787/nydha-2226-7425-2018-20-12-65-69
- Balkarov AO, Kardanova SY, Hulaev IV, et al. The state of the mucous membrane of the oral cavity of persons used by removable prostheses. Modern Problems of Science and Education. 2018;(5):83. (In Russ). doi: 10.17513/spno.28116
- Korol DM, Apekunov GY, Belyj SN, Onipko EL. Schiller’s test improvement to assess the state of oral mucosa around endoosseous implants. Privolzhskii nauchnyi vestnik. 2013;(11):142–145. (In Russ).
- Guyter O, Oleinikov A, Mzhavanadze N, Kalinovsky S. Application of oral mucosa staining for control of late inflammatory effects at the stage of formation of a prosthetic body using immediat-prostheses. Georgian Med News. 2021;(9):43–49. (In Russ).
- Kouadio AA, Jordana F, Koffi NJ, et al. The use of laser Doppler flowmetry to evaluate oral soft tissue blood flow in humans: A review. Arch Oral Biol. 2018;86:58–71. doi: 10.1016/j.archoralbio.2017.11.009
- Rabinovich OF, Rabinovich IM, Abramova ES. The role of cytokines and immunoglobulins of the oral fluid in the genesis of autoimmune diseases of the oral mucosa. Stomatologiya. 2019;98(6–2):4245. (In Russ). doi: 10.17116/stomat20199806242
- Strelnikova EA, Trushkina PYu, Surov IYu, et al. Endothelium in vivo and in vitro. Part 1: histogenesis, structure, cytophysiology and key markers. Nauka molodykh (Eruditio Juvenium). 2019;7(3):450–465. (In Russ). doi: 10.23888/HMJ201973450-465
- Tlustenko VP, Bayrikov IM, Trunin DA, et al. Influence of dental prosthetics technology on the dynamics of early predictors of destructive inflammatory process in the peri-implant zone. Vestnik RGMU. 2019;(2):44–47. (In Russ). doi: 10.24075/vrgmu.2019.025
- Amkhadova MA, Mustafaev NM, Amkhadov IS. Sostoyanie regionarnogo krovotoka v slizistoi obolochke desny do i posle kostno-plasticheskoi operatsii u patsientov so znachitel’noi atrofiei al’veolyarnogo otrostka chelyustei. Sovremennaya stomatologiya: problemy, zadachi, resheniya. Tver: Tver State Medical Academy; 2015. P:77–81. (In Russ).
- Kokovic V, Krsljak E, Andric M, et al. Correlation of bone vascularity in the posterior mandible and subsequent implant stability: a preliminary study. Implant Dent. 2014;23(2):200–205. doi: 10.1097/ID.0000000000000057
- Kang DY, Kim M, Lee SJ, et al. Early implant failure: a retrospective analysis of contributing factors. J Periodontal Implant Sci. 2019;49(5):287–298. doi: 10.5051/jpis.2019.49.5.287
- Yanishen IV, Fedotova OL, Khlystun NL. The effect analysis of the double-layer bases in removable dentures with occlusive part on the microcirculatory state of the denture foundation area vessels. World of Medicine and Biology. 2020;(2):142–145. doi: 10.26724/2079-8334-2020-2-72-142-145
- Kulchikov AE, Morozov SG, Musin RS, Grinenko EA. Experimental study on disorders in the activity of macrophages in the acute period of different severities of cerebral stroke. I.P. Pavlov Russian Medical Biological Herald. 2021;29(2):201–212. (In Russ). doi: 10.17816/PAVLOVJ57821
- Durnovo EA, Bespalova NA, Yanova NA, Korsakova AI. Analysis of surgical methods for increasing the width of the keratinized attached gingiva. Nauchnyi posyl vysshei shkoly — real’nye dostizheniya prakticheskogo zdravookhraneniya. Nizhny Novgorod: Remedium Privolzhye; 2018. P:146–156. (In Russ).