Profilometric analysis of cross-linked collagen matrix for soft tissue thickness augmentation in dental implants: A randomized controlled clinical trial

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Abstract

BACKGROUND: Dental implantation is an effective method for rehabilitating patients without teeth. The long-term survival of implants is influenced by various factors, one of which is the condition of the soft tissue surrounding the implant.

AIM: To evaluate the effectiveness of cross-linked collagen matrix for soft tissue augmentation in the implant area.

MATERIALS AND METHODS: Thirty-two patients with soft tissue thickness deficiency were examined. The patients were divided into two groups depending on the method of surgery. Group 1 received a cross-linked collagen matrix, whereas group 2 underwent the transplantation of a free connective tissue graft. The increase in soft tissue thickness was assessed 3 and 6 months after surgery.

RESULTS: Soft tissue thickness 3 months after surgery increased by 1.77±0.61 and 1.26±0.41 mm in groups 1 and 2, respectively (p <0.001). Moreover, 6 months after surgery, soft tissue thickness increased by 1.11±0.44 and 1.43±0.81 mm compared with the initial value (p=0.012).

CONCLUSION: The use of the collagen matrix increases the soft tissue thickness in the implant area; however, the effect size is lower than that obtained by autograft transplantation.

About the authors

Igor P. Ashurko

Sechenov First Moscow State Medical University (Sechenov University)

Author for correspondence.
Email: ashurko@yandex.ru
ORCID iD: 0000-0001-9862-2657
SPIN-code: 5337-0985

MD, Cand. Sci. (Med.), Assistant Professor

Russian Federation, 11 Mozhaiskii Val street, 121059 Moscow

Anna I. Galyas

Sechenov First Moscow State Medical University (Sechenov University)

Email: anngalyas@gmail.com
ORCID iD: 0000-0003-0561-3984
SPIN-code: 5536-1047

Postgraduate Student

Russian Federation, 11 Mozhaiskii Val street, 121059 Moscow

Mary L. Magdalyanova

Sechenov First Moscow State Medical University (Sechenov University)

Email: magdalyanovamary@mail.ru
ORCID iD: 0000-0001-9910-7227
SPIN-code: 5696-5046

Resident

Russian Federation, 11 Mozhaiskii Val street, 121059 Moscow

Maxim V. Balyasin

Peoples’ Friendship University of Russia

Email: b.maxim4432@yandex.ru
ORCID iD: 0000-0002-3097-344X
SPIN-code: 9738-4520

Junior Research Associate

Russian Federation, 6 Miklukho-Maklaya street, 117198 Moscow

Bekhruz B. Rasamatov

Sechenov First Moscow State Medical University (Sechenov University)

Email: behruzrasamatovmoskva@gmail.com
ORCID iD: 0000-0003-4647-0668

student

Russian Federation, 11 Mozhaiskii Val street, 121059 Moscow

Sabina V. Kazumyan

Sechenov First Moscow State Medical University (Sechenov University)

Email: sabina.kazumyan@yandex.ru
ORCID iD: 0000-0002-1420-0770

student 

Russian Federation, 11 Mozhaiskii Val street, 121059 Moscow

Svetlana V. Tarasenko

Sechenov First Moscow State Medical University (Sechenov University)

Email: prof_tarasenko@rambler.ru
ORCID iD: 0000-0001-8595-8864
SPIN-code: 3320-0052

MD, Dr. Sci. (Med.), Professor, Head of the Department

Russian Federation, 11 Mozhaiskii Val street, 121059 Moscow

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2. Fig. 1. Projection of the postoperative soft tissue contour overlaid on the cone beam computed tomography data: a — after 3 months; b — after 6 months.

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