Profilometric analysis of cross-linked collagen matrix for soft tissue thickness augmentation in dental implants: A randomized controlled clinical trial

封面

如何引用文章

全文:

开放存取 开放存取
受限制的访问 ##reader.subscriptionAccessGranted##
受限制的访问 订阅存取

详细

BACKGROUND: Dental implantation is an effective method for rehabilitating patients without teeth. The long-term survival of implants is influenced by various factors, one of which is the condition of the soft tissue surrounding the implant.

AIM: To evaluate the effectiveness of cross-linked collagen matrix for soft tissue augmentation in the implant area.

MATERIALS AND METHODS: Thirty-two patients with soft tissue thickness deficiency were examined. The patients were divided into two groups depending on the method of surgery. Group 1 received a cross-linked collagen matrix, whereas group 2 underwent the transplantation of a free connective tissue graft. The increase in soft tissue thickness was assessed 3 and 6 months after surgery.

RESULTS: Soft tissue thickness 3 months after surgery increased by 1.77±0.61 and 1.26±0.41 mm in groups 1 and 2, respectively (p <0.001). Moreover, 6 months after surgery, soft tissue thickness increased by 1.11±0.44 and 1.43±0.81 mm compared with the initial value (p=0.012).

CONCLUSION: The use of the collagen matrix increases the soft tissue thickness in the implant area; however, the effect size is lower than that obtained by autograft transplantation.

作者简介

Igor Ashurko

Sechenov First Moscow State Medical University (Sechenov University)

编辑信件的主要联系方式.
Email: ashurko@yandex.ru
ORCID iD: 0000-0001-9862-2657
SPIN 代码: 5337-0985

MD, Cand. Sci. (Med.), Assistant Professor

俄罗斯联邦, 11 Mozhaiskii Val street, 121059 Moscow

Anna Galyas

Sechenov First Moscow State Medical University (Sechenov University)

Email: anngalyas@gmail.com
ORCID iD: 0000-0003-0561-3984
SPIN 代码: 5536-1047

Postgraduate Student

俄罗斯联邦, 11 Mozhaiskii Val street, 121059 Moscow

Mary Magdalyanova

Sechenov First Moscow State Medical University (Sechenov University)

Email: magdalyanovamary@mail.ru
ORCID iD: 0000-0001-9910-7227
SPIN 代码: 5696-5046

Resident

俄罗斯联邦, 11 Mozhaiskii Val street, 121059 Moscow

Maxim Balyasin

Peoples’ Friendship University of Russia

Email: b.maxim4432@yandex.ru
ORCID iD: 0000-0002-3097-344X
SPIN 代码: 9738-4520

Junior Research Associate

俄罗斯联邦, 6 Miklukho-Maklaya street, 117198 Moscow

Bekhruz Rasamatov

Sechenov First Moscow State Medical University (Sechenov University)

Email: behruzrasamatovmoskva@gmail.com
ORCID iD: 0000-0003-4647-0668

student

俄罗斯联邦, 11 Mozhaiskii Val street, 121059 Moscow

Sabina Kazumyan

Sechenov First Moscow State Medical University (Sechenov University)

Email: sabina.kazumyan@yandex.ru
ORCID iD: 0000-0002-1420-0770

student 

俄罗斯联邦, 11 Mozhaiskii Val street, 121059 Moscow

Svetlana Tarasenko

Sechenov First Moscow State Medical University (Sechenov University)

Email: prof_tarasenko@rambler.ru
ORCID iD: 0000-0001-8595-8864
SPIN 代码: 3320-0052

MD, Dr. Sci. (Med.), Professor, Head of the Department

俄罗斯联邦, 11 Mozhaiskii Val street, 121059 Moscow

参考

  1. World Health Organization [Internet]. Oral health. Available from: https://www.who.int/news-room/fact-sheets/detail/oral-health
  2. Thoma DS, Gasser TJW, Hämmerle CHF, Strauss FJ, Jung RE. Soft tissue augmentation with a volume-stable collagen matrix or an autogenous connective tissue graft at implant sites: Five-year results of a randomized controlled trial post implant loading. J Periodontol. 2023;94(2):230–243. doi: 10.1002/JPER.22-0226
  3. Monje A, Kan JY, Borgnakke W. Impact of local predisposing/precipitating factors and systemic drivers on peri-implant diseases. Clin Implant Dent Relat Res. Published online 2022 Dec 19. doi: 10.1111/cid.13155
  4. Puzio M, Hadzik J, Błaszczyszyn A, Gedrange T, Dominiak M. Soft tissue augmentation around dental implants with connective tissue graft (CTG) and xenogenic collagen matrix (XCM). 1-year randomized control trail. Ann Anat. 2020;230:151484. doi: 10.1016/j.aanat.2020.151484
  5. Kulakov AA, Badalyan VA, Parinov DA, Martirosova AYu. Modern approaches to increase the volume of soft tissues in the area of teeth and implants using connective tissue grafts. Mezhdunarodnyi zhurnal prikladnykh i fundamental’nykh issledovanii. 2020;(2):69–73. (In Russ). doi: 10.17513/mjpfi.13012
  6. Thoma DS, Gil A, Hämmerle CHF, Jung RE. Management and prevention of soft tissue complications in implant dentistry. Periodontol 2000. 2022;88(1):116–129. doi: 10.1111/prd.12415
  7. Thoma DS, Naenni N, Figuero E, et al. Effects of soft tissue augmentation procedures on peri-implant health or disease: A systematic review and meta-analysis. Clin Oral Implants Res. 2018;29 Suppl. 15:32–49. doi: 10.1111/clr.13114
  8. Ashurko I, Tarasenko S, Esayan A, et al. Connective tissue graft versus xenogeneic collagen matrix for soft tissue augmentation at implant sites: a randomized-controlled clinical trial. Clin Oral Investig. 2022;26(12):7191–7208. doi: 10.1007/s00784-022-04680-x
  9. Melezhechkina IA, Atrushkevich VG, Berchenko GN. Comparative morphological assessment of crosslinked and non-crosslinked xenograft biointegration quality. Parodontologiya. 2022;27(4):288–297. doi: 10.33925/1683-3759-2022-27-4-288-297
  10. Vallecillo C, Toledano-Osorio M, Vallecillo-Rivas M, et al. Collagen matrix vs. autogenous connective tissue graft for soft tissue augmentation: A systematic review and meta-analysis. Polymers. 2021;13(11):1810. doi: 10.3390/polym13111810
  11. Gargallo-Albiol J, Barootchi S, Tavelli L, Wang HL. Efficacy of xenogeneic collagen matrix to augment peri-implant soft tissue thickness compared to autogenous connective tissue graft: A systematic review and meta-analysis. Int J Oral Maxillofac Implants. 2019;34(5):1059–1069. doi: 10.11607/jomi.7497
  12. Lin GH, Madi IM. Soft-tissue conditions around dental implants: A literature review. Implant Dent. 2019;28(2):138–143. doi: 10.1097/ID.0000000000000871
  13. Cairo F, Barbato L, Tonelli P, et al. Xenogeneic collagen matrix versus connective tissue graft for buccal soft tissue augmentation at implant site. A randomized, controlled clinical trial. J Clin Periodontol. 2017;44(7):769–776. doi: 10.1111/jcpe.12750
  14. De Angelis P, De Angelis S, Passarelli PC, et al. Clinical comparison of a xenogeneic collagen matrix versus subepithelial autogenous connective tissue graft for augmentation of soft tissue around implants. Int J Oral Maxillofac Surg. 2021;50(7):956–963. doi: 10.1016/j.ijom.2020.11.014
  15. Ashurko IP, Tarasenko SV, Esayan AV, Galyas AI, Li AV. Evaluation of free connective tissue graft and collagen matrix clinical effectiveness to increase soft tissue thickness around dental implants. Parodontologiya. 2022;27(2):117–125. doi: 10.33925/1683-3759-2022-27-2-117-125
  16. Sanz-Martín I, Rojo E, Maldonado E, et al. Structural and histological differences between connective tissue grafts harvested from the lateral palatal mucosa or from the tuberosity area. Clin Oral Investig. 2019;23(2):957–964. doi: 10.1007/s00784-018-2516-9
  17. Thoma DS, Strauss FJ, Mancini L, Gasser TJW, Jung RE. Minimal invasiveness in soft tissue augmentation at dental implants: A systematic review and meta-analysis of patient-reported outcome measures. Periodontol 2000. 2023;91(1):182–198. doi: 10.1111/prd.12465
  18. Hadzik J, Błaszczyszyn A, Gedrange T, Dominiak M. Soft-tissue augmentation around dental implants with a connective tissue graft (CTG) and xenogeneic collagen matrix (CMX)—5-year follow-up. J Clin Med. 2023;12(3):924. doi: 10.3390/jcm12030924
  19. Sarkisyan VM, Zayratyants OV, Panin AM, Panin MG. Morphological singularities of the various gingival biotypes. Parodontologiya. 2012;17(1):26–29.
  20. Eghbali A, De Bruyn H, Cosyn J, Kerckaert I, Van Hoof T. Ultrasonic assessment of mucosal thickness around implants: validity, reproducibility, and stability of connective tissue grafts at the buccal aspect. Clin Implant Dent Relat Res. 2016;18(1):51–61. doi: 10.1111/cid.12245

补充文件

附件文件
动作
1. JATS XML
下载
2. Fig. 1. Projection of the postoperative soft tissue contour overlaid on the cone beam computed tomography data: a — after 3 months; b — after 6 months.

下载 (221KB)
索引源数据

版权所有 © Eco-Vector, 2024

Creative Commons License
此作品已接受知识共享署名-非商业性使用-禁止演绎 4.0国际许可协议的许可。
 


##common.cookie##