Clinical effectiveness of a new collagen-based drug with lincomycin for the prevention and treatment of jaw alveolitis

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Abstract

BACKGROUND: Alveolitis is the most common complication that occurs after tooth extraction. Among preventive and therapeutic methods, pharmacological agents for the dry socket treatment have been proposed. However, the “gold standard” for the prevention and treatment of alveolitis has not been defined.

AIM: The study aimed to conduct a comparative analysis of the effectiveness of a collagen sponge with lincomycin and an iodoform tampon for the prevention of the development and treatment of alveolitis.

MATERIAL AND METHODS: The study included 75 patients with jaw alveolitis and patients with teething disorders and chronic periodontitis who underwent planned tooth extraction. The patients were divided into two groups: group 1 underwent a socket revision, whereas group 2 had a tooth extraction. The patients of each group were divided into two subgroups: subgroup A used a collagen sponge with lincomycin and subgroup B used an iodoform tampon. The intensity of pain syndrome, severity of mucosal hyperemia, and collateral edema were assessed, and the epithelialization time of the sockets was recorded.

RESULTS: The clinical study of the effectiveness of a collagen sponge with lincomycin in comparison with an iodoform tampon demonstrated some advantages of a collagen sponge, including a more comfortable postoperative period, mild pain, less pronounced edema and hyperemia, epithelialization of the extracted teeth sockets 1.5 days earlier.

CONCLUSION: For the prevention and treatment of alveolitis, especially in patients in whom the use of iodine compounds is contraindicated, the use of “Alvanes” collagen sponge with lincomycin is preferable to an iodoform tampon.

About the authors

Svetlana V. Tarasenko

First Moscow State Medical University (Sechenov University)

Email: prof_tarasenko@rambler.ru
ORCID iD: 0000-0001-8595-8864

MD, Dr, Sci. (Med.), professor

Russian Federation, 2, Bolshaya Pirogovskaya str., Moscow, 119991

Nikolai V. Muravev

First Moscow State Medical University (Sechenov University)

Author for correspondence.
Email: 163789789@mail.ru
ORCID iD: 0000-0003-4667-4783
SPIN-code: 8275-9770

postgraduate student

Russian Federation, 2, Bolshaya Pirogovskaya str., Moscow, 119991

Bagrat R. Khurkhurov

Dental Polyclinic № 23

Email: khurkhurov@yandex.ru
ORCID iD: 0000-0003-1041-8235

MD, Cand. Sci. (Med.)

Russian Federation, Moscow

Anna M. Ershova

Dental clinic "Denta Vita Prestige"

Email: annushka1412@mail.ru
ORCID iD: 0000-0001-9266-846X

MD, Cand. Sci. (Med.)

Russian Federation, Moscow

Evgeniy V. Ippolitov

Moscow State Medical and Dental University named after A.I. Evdokimov

Email: ippo@bk.ru
ORCID iD: 0000-0003-1737-0887

MD, Dr, Sci. (Med.), professor

Russian Federation, Moscow

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Copyright (c) 2022 Tarasenko S.V., Muravev N.V., Khurkhurov B.R., Ershova A.M., Ippolitov E.V.

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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
 


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