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RADIOFREQUENCY ABLATION IN TREATMENT OF GASTROESOPHAGEAL REFLUX DISEASE WITH BARRETT’S ESOPHAGUS
- Authors: Puchkov KV1, Khabarova EV2, Tishchenko ES2
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Affiliations:
- Ryazan State Medical University named after academician I.P. Pavlov
- Swiss University Clinic
- Issue: Vol 21, No 1 (2019)
- Pages: 117-122
- Section: Articles
- URL: https://journals.rcsi.science/1682-7392/article/view/13062
- DOI: https://doi.org/10.17816/brmma13062
- ID: 13062
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Abstract
OBJECTIVE: To evaluate results of treatment of patients with Barrett’s esophagus, including radiofrequency ablation of columnar epithelium with antireflux surgery. METHODS: We treated82 patients with gastroesophageal reflux disease withBarrett’s esophagus between 2011 and 2018. 4 patients had low-grade dysplasia, 63 patients had hiatal hernia. We performed laparoscopic Toupet 2700 fundoplication in 58 of these patients.This allowedto perform radiofrequency ablation (RFA) procedure 2-3 months later in 27 of these patients. In 12 patients without radiological signs of hiatal hernia we performed RFA as the first treatment step. Follow-up endoscopy was performed 3,6 and 12 months after RFA. RESULTS: Metaplasia eradication wasachieved in 97,5% after 1 procedure and in 100% after 2 procedures. 6 months after treatment recurrence of metaplasia was registered in 2,4% patients. CONCLUSIONS: Changing security profile of new endoscopic treatment methods indicates the need for new strategies for Barrett’s esophagus. The most effective scheme is two-step treatment including antireflux surgery and radiofrequency ablation in combination with drug therapy.
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##article.viewOnOriginalSite##About the authors
K V Puchkov
Ryazan State Medical University named after academician I.P. PavlovRyazan, Russia
E V Khabarova
Swiss University ClinicNikoloyamskaya str. 19-1, Moscow, Russia
E S Tishchenko
Swiss University ClinicNikoloyamskaya str. 19-1, Moscow, Russia
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