DIAGNOSTICCRITERIAANDMANAGMENTOF ACUTE CHOLANGITIS AND BILIARY SEPSIS: THE MODERN VIEW ON THE PROBLEM


Cite item

Full Text

Abstract

Theproblemofcholangitisandbiliarysepsisbecomemoreandmoreactual.Developingdiagnosticcriteriaforpatientswithinflammationofbiliarytractisoneofunsolvedquestionsofbiliarysurgery. Accordingtonewclassificationofgeneralizedformofinfections (Sepsis 3) it’sadvisabletoclassifiedpatients with biliary obstruction to three groups: mechanical jaundice, acute cholangitis and biliary sepsis with defying appropriate diagnostic criteria for each of them.Theaimofourworkistoimprovetreatmentresultsforpatientswithhyperbilirubinemia, biliary hypertension and system inflammation response syndrome (SIRS) by dividing them on groups and determining diagnostic criteria for each of them. Intheperiodfrom 2014 to 2018 wehavetreated 208 patientswithbiliaryobstruction. Accordingtodevelopeddiagnosticcriteriaallpatients was divided on three groups: mechanical jaundice, acute cholangitis and biliary sepsis.Afterthetreatmentthenextvalueswereanalyzed: timefromadmissiontohospitaltooperation, thetimeofoperation, thefrequencyofpostoperativecomplications, mortality, the duration of hospital stay, economic efficiency.Toassesstheeffectivesofdevelopedcriteriacomparativeanalysiswithretrospectivegroup, whichcontained 182 patients with hyperbilirubinemia, biliary hypertension and SIRS treated in a period from 2010 to 2014, was performed. Accordingtoobtainedresultswecanconcludethatdividingpatientswithhyperbilirubinemia, biliary hypertension and SIRS on groups and developeddiagnosticcriteria, routing and manage tactics let us to improve treatment results in this category of patients, about what we can judge by such figures as timefromadmissiontohospitaltooperation, thefrequencyofpostoperativecomplications, mortality, the duration of hospital stay, economic efficiency.

About the authors

A Yu Korolkov

Pavlov First Saint Petersburg State Medical University

197022, L’vaTolstogosrt. 6-8, Saint-Petersburg, Russia

D N Popov

Pavlov First Saint Petersburg State Medical University

197022, L’vaTolstogosrt. 6-8, Saint-Petersburg, Russia

M A Kitaeva

Pavlov First Saint Petersburg State Medical University

197022, L’vaTolstogosrt. 6-8, Saint-Petersburg, Russia

A O Tantsev

Pavlov First Saint Petersburg State Medical University

197022, L’vaTolstogosrt. 6-8, Saint-Petersburg, Russia

References

  1. Малахова И.Г., Шкляев А.Е., Уткин И.Ю. Острый холангит, осложнённый билиарным сепсисом: Клинический случай с благоприятным исходом //Архивъвнутренней медицины. 2016.№4. С. 65 - 69.
  2. Хацко В.В., Потапов В.В., Зенин О.К.Билиарный сепсис желчнокаменной этиологии // Медицинские науки. 2016. № 3. С.62 - 67.
  3. Тарасенко С.В.,Зайцев О.В., Тюленев Д.О. Распространённость осложнённых форм желчекаменной болезни // Наука молодых (EruditioJuvenium). 2018. № 2. С. 218 - 224.
  4. Багненко С.Ф., Шляпников С.А., Корольков А.Ю. Современные подходы к этиологии, патогенезу и лечению холангита и билиарного сепсиса // Бюллетень сибирской медицины.2007.№ 3.- С.12 - 15.
  5. Борисов А.Е., Кащенко В.А., Кубачев К.Г. Пути оптимизации стандартов лечения острого холецистита // Вестник хирургии им. И.И. Грекова. 2012. № 6. С. 80 - 85.
  6. Masamichi Y.,Jiro H., Tadahiro T. Tokyo Guidelines 2018: diagnostic criteria and severity grading of acute cholecystitis // J Hepatobiliary Pancreat Sci. 2018. № 25. Р.41-54.doi: 10.1002/jhbp.526
  7. Vincent L., Tracey K. Sepsis definitions: time for change //Lancet.2013. Vol. 381.№5. P. 774 - 775. doi: 10.1016/s0140-6736(12)61815-7
  8. Singer M. The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3) //JAMA. 2016. Vol. 315. N3. P. 801-810.doi: 10.1001/jama.2016.0287

Copyright (c) 2019 Korolkov A.Y., Popov D.N., Kitaeva M.A., Tantsev A.O.

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies