The method of combined use of enzyme therapy and carboxytherapy in the correction of complications after injection of polylactic acid in cosmetology

Objective. To study the effectiveness of the combined method, including the course of colladizine diadynamophoresis 1000 KE (collagenase units) in combination with injection carboxytherapy in the correction of complications that occurred when superficial administration of polylactic acid into the skin.

Material and methods. Under observation were 38 women of 32 to 39 years old with a complication after the introduction of a filler based on polylactic acid with localization in the abdomen. Three groups were identified that received a course of carboxytherapy, a course of collagenase diadynamophoresis, and their combination.

Results. The use of the combined course of Collizin diadynamophoresis with injection carboxytherapy provides a pronounced analgesic effect, improves microcirculation, stabilizes the psycho-emotional state and gives a pronounced effect of reducing the thickness of the dermis and increasing the density coefficient of the dermis, which is probably associated with a decrease in intradermal edema, which occurs as a reaction to superficially introduced filler. In addition, this combined technique significantly accelerates the biodegradation of the surface-injected filler and affects pathological fibrosis around polylactic acid.

Conclusions. The combined use of collizine diadynamophoresis and injection carboxytherapy locally on the lesion sites with complications such as surface administration of a filler based on polylactic acid is a highly effective treatment method, which is confirmed by the relief of clinical symptoms and an increase in the quality of life of patients.