Experience in the application of non-invasive neuromodulation in the angioneurology

Cover Page

Cite item

Full Text

Abstract

The electromagnetic field is a fundamental factor of objective reality, when exposed to the brain causes the appearance and development of a complex of functional changes that help in the study of the properties of the nervous system itself. Non-invasive neuromodulation is a therapeutic exogenous effect on various parts of the nervous system (mainly vegetative) with the help of electromagnetic physical (electric, magnetic) factors in the course of drug therapy in accordance with the standards of care specifically for each nosological form. The article discusses the role of interhemispheric asymmetry in the pathogenesis of cerebrovascular diseases and effectiveness of the method of transcranial electrostimulation with feedback in the form of electroencephalography using the apparatus TATOS in the rehabilitation of patients with cerebrovascular pathology, including early recovery period of ischemic stroke

Purpose: to identify clinical and neurophysiological features in patients with cerebrovascular pathology during transcranial electrotherapy with feedback.

Material and methods. Total 105 patients with vascular pathology of the brain were studied, including 35 patients after ischemic stroke in the early recovery period with mild or moderate neurological symptoms, 70 patients with chronic cerebrovascular insufficiency. The average age is 56 ± 3.6 years old. A comprehensive clinical, neurophysiological, and neuroimaging study was conducted. The course of non-invasive neuromodulation was performed against the background of medical treatment in accordance with the medical standards with the use of a pulse generator TETOS with feedback in the form of electroencephalography.

Results. The study of the parameters of neurodynamic interhemispheric asymmetry showed that in patients who underwent onmc in the left middle cerebral artery basin, the localization of the ischemic lesion in the right middle cerebral artery basin was observed in the form of an increase in the interhemispheric coherence of the main electro-encephalographical rhythms with a predominance of slow-wave activity. After a course of non-invasive neuromodulation, the majority of patients in the main group noted an improvement in their well-being: headaches, dizziness, irritability, anxiety and anxiety, tension, significantly improved emotional state, and sleep normalized. The study of parameters of dynamic interhemispheric asymmetry has shown that when conducting transcranial electrotherapy with feedback in patients who have undergone stroke, depending on the localization, its decrease is noted, as well as normalization of the distribution of alpha rhythm in zones, depending on the localization of the focus.

Conclusions. The overall assessment of the effect of treatment in the whole group revealed a clear prevalence of positive results when using TАTOS-therapy.

About the authors

Alexey A. Voropaev

National Medical Research Center for Rehabilitation and Balneology of the Ministry of Health

Author for correspondence.
Email: woropaew@ya.ru
ORCID iD: 0000-0003-0944-8234
SPIN-code: 4646-4268

PhD

Russian Federation, Moscow

Galina E. Ivanova

Pirogov Russian National Research Medical University of the Ministry of Health

Email: woropaew@ya.ru
SPIN-code: 4049-4581

MD, PhD, Professor

Russian Federation, Moscow

Tatiana V. Nikolaeva

Main Military Clinical Hospital named after N.N. Burdenko of the Ministry of Defense of the Russia

Email: woropaew@ya.ru

врач анестезиолог-реаниматолог ФГБУ «Главный военный клинический госпиталь им. Н.Н. Бурденко» Минобороны России

Russian Federation, Moscow

References

  1. Gusev EI, Konovalov AN, Burd GS. Methods of research in neurology and neurosurgery: Guide for doctors. Moscow; 2000. (In Russ.)
  2. Grindel OM, Shchekutyev GA, et al. Neurophysiological research in clinical practice: Monography. Moscow; 2005. (In Russ.)
  3. Akhapkin RV, Akhapkina VI. Modulator concept as an innovative trend in medicine. Rossiiskii meditsinskii zhurnal. 2012;(19):962-958. (In Russ.)
  4. Certificate of registration of the computer program RUS 2003611167. Voropaev AA. Program for controlling the output parameters of the device for transcranial electrical stimulation. (In Russ.)
  5. Certificate of registration of the computer program RUS 2005611926. Voropaev AA. Program for controlling the output parameters of devices for low-frequency electro-magnetic therapy (STIM 7). (In Russ.)
  6. Patent for invention RUS 2300397 C2, 10.06.2007. Voropaev AA. Method of treating neuroses. (In Russ.)
  7. Voropaev AA, Mochalov AD. Transcranial electrostimulation in chronic cerebral vascular insufficiency. S.S. Korsakov Journal of Neurology and Psychiatry. 2006;106(5):31-34. (In Russ.)
  8. Patent for invention RUS 2233677 C2, 10.08.2004. Voropaev AA, Mochalov AD, Zhirnova EV. Method of treatment of vascular headaches. (In Russ.)
  9. Patent for invention RU 2297253 C2, 20.04.2007. Voropaev AA, Shtro R. Transcranial electrostimulator (variants) and device for attaching electrodes of transcranial electrostimulator. (In Russ.)
  10. Zhivolupov CA, Samartsev IN, Syroezhkin FA. Contemporary conception of neuroplasticity (theoretical aspects and practical significance). S.S. Korsakov Journal of Neurology and Psychiatry. 2013;113(10):102-108. (In Russ.)
  11. Ivanova GE. Medical rehabilitation in Russia. Development prospects. Bulletin of Rehabilitation Medicine. 2013;(5):3-8. (In Russ.)
  12. Ivanova GE. Organization of rehabilitation process. Kremlin Medicine Journal. 2012;(4):8-10. (In Russ.)
  13. Ivanova GE. Vosstanovitel'noe lechenie bol'nykh s insul'tom. Rossiiskii meditsinskii zhurnal. 2002;(1):48. (In Russ.)
  14. Sharova EV, Melnikov AV, Novikova MR, et al. Changes in the brain spontaneous bioelectrical activity during transcranial electrical and electromagnetic stimulation. I.P. Pavlov Journal of Higher Nervous Activity. 2006;56(3):344-351. (In Russ.)
  15. Non-invasive neuromodulation of the central nervous system: Оpportunities and Challenges: Workshop Summary. Washington D.C., 2015. doi: 10.17226/21767

Supplementary files

Supplementary Files
Action
1. JATS XML
2. Fig. Pathological asymmetry in stroke

Download (121KB)

Copyright (c) 2019 Eco-Vector


 


This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies