Personalized method of treatment of patients with complications after contouring of the nasolacrimal sulcus

BACKGROUND: Contouring of the nasolacrimal sulcus area is becoming an increasingly popular procedure due to the rapid onset of a pronounced aesthetic result, however, in recent years there has been an increase in the pool of complications both in the early and late post-injection recovery period. At the same time, there are no differentiated approaches to the choice of physiotherapy techniques and their combinations depending on the genetic profile of the patient and the clinical and functional picture of the complication.

AIM: to develop and evaluate the use of personalized physiotherapy in patients with complications after the introduction of fillers based on stabilized hyaluronic acid, taking into account their genetic predisposition.

MATERIAL AND METHODS: The analyzed data of the study of 47 patients, average age 35.7±10.2, with a diagnosis of "L57.4 Senile atrophy (lethargy) of the skin", who received late complications (local edema, filler contouring, sensitivity change at the filler injection site) after the introduction of a filler based on stabilized hyaluronic acid in the nasolabial furrow area. All patients underwent genetic testing on the Cosmetology panel before the start of treatment. There were 3 groups that received longidase diadinamophoresis, injection carboxytherapy of the nasolacrimal sulcus area or a combination of the above techniques.

RESULTS: When using a combined course of longidase diadinamophoresis and injection carboxytherapy, there was a significant decrease in clinical manifestations in the form of conturation, local edema and neuropathy, the psychoemotional state of patients stabilized. In addition, the therapeutic complex significantly accelerated the biodegradation of the filler and has a restructuring effect on the skin of the nasolacrimal furrow, reducing the thickness of the dermis. increasing the density coefficient of the dermis and accelerating the biodegradation of the superficially injected compared to other study groups.

CONCLUSION: The personalized combined use of the method, including a course of longidase diadinamophoresis and injectable carboxytherapy for the correction of complications of contouring of the nasolacrimal sulcus area with fillers based on stabilized hyaluronic acid in the form of local edema, neuropathy and filler contouring, is a highly effective treatment method, which is confirmed by the relief of clinical symptoms, acceleration of biodegradation of the drug and improvement of the quality of life of patients.