电邮这篇文章 Peroxide-Induced Oxidative Modification of Hemoglobin
- 作者: Vasilyeva A.D.1, Yurina L.V.1, Bugrova A.E.1, Indeykina M.I.1,2, Azarova D.Y.1,3, Bychkova A.V.1, Akzhigitova K.I.1,4, Kononikhin A.S.1,5,2, Nikolaev E.N.1,5,6, Rosenfeld M.A.1
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隶属关系:
- Emanuel Institute of Biochemical Physics, Russian Academy of Sciences
- Moscow Institute of Physics and Technology
- Skryabin Moscow State Academy of Veterinary Medicine, and Biotechnology
- Belinsky Pedagogical Institute, Penza State University
- Tal’roze Institute for Energy Problems of Chemical Physics, Russian Academy of Sciences
- Skolkovo Institute of Science and Technology
- 期: 卷 486, 编号 1 (2019)
- 页面: 197-200
- 栏目: Biochemistry, Biophysics, and Molecular Biology
- URL: https://journals.rcsi.science/1607-6729/article/view/213012
- DOI: https://doi.org/10.1134/S1607672919030116
- ID: 213012
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详细
The oxidative modification of human hemoglobin (Hb) treated with hydrogen peroxide was investigated. Using the mass spectrometry method, the oxidized amino acid residues of the hemoglobin molecule were detected: αTrp14, αTyr24, αArg31, αMet32, αTyr42, αHis45, αHis72, αMet76, αPro77, αLys90, αCys104, αTyr140, βHis2, βTrp15, βTrp37, βMet55, βCys93, βCys112, βTyr130, βLys144, and βHis146. The antioxidant potential of the Hb molecule in the intracellular space and in the blood plasma is discussed.
作者简介
A. Vasilyeva
Emanuel Institute of Biochemical Physics, Russian Academy of Sciences
编辑信件的主要联系方式.
Email: ms.kadaver@mail.ru
俄罗斯联邦, Moscow, 119334
L. Yurina
Emanuel Institute of Biochemical Physics, Russian Academy of Sciences
Email: ms.kadaver@mail.ru
俄罗斯联邦, Moscow, 119334
A. Bugrova
Emanuel Institute of Biochemical Physics, Russian Academy of Sciences
Email: ms.kadaver@mail.ru
俄罗斯联邦, Moscow, 119334
M. Indeykina
Emanuel Institute of Biochemical Physics, Russian Academy of Sciences; Moscow Institute of Physics and Technology
Email: ms.kadaver@mail.ru
俄罗斯联邦, Moscow, 119334; Dolgoprudnyi, Moscow oblast, 141701
D. Azarova
Emanuel Institute of Biochemical Physics, Russian Academy of Sciences; Skryabin Moscow State Academy of Veterinary Medicine, and Biotechnology
Email: ms.kadaver@mail.ru
俄罗斯联邦, Moscow, 119334; Moscow
A. Bychkova
Emanuel Institute of Biochemical Physics, Russian Academy of Sciences
Email: ms.kadaver@mail.ru
俄罗斯联邦, Moscow, 119334
K. Akzhigitova
Emanuel Institute of Biochemical Physics, Russian Academy of Sciences; Belinsky Pedagogical Institute, Penza State University
Email: ms.kadaver@mail.ru
俄罗斯联邦, Moscow, 119334; Penza
A. Kononikhin
Emanuel Institute of Biochemical Physics, Russian Academy of Sciences; Tal’roze Institute for Energy Problems of Chemical Physics, Russian Academy of Sciences; Moscow Institute of Physics and Technology
Email: ms.kadaver@mail.ru
俄罗斯联邦, Moscow, 119334; Moscow, 119334; Dolgoprudnyi, Moscow oblast, 141701
E. Nikolaev
Emanuel Institute of Biochemical Physics, Russian Academy of Sciences; Tal’roze Institute for Energy Problems of Chemical Physics, Russian Academy of Sciences; Skolkovo Institute of Science and Technology
Email: ms.kadaver@mail.ru
俄罗斯联邦, Moscow, 119334; Moscow, 119334; Skolkovo, Moscow oblast, 143025
M. Rosenfeld
Emanuel Institute of Biochemical Physics, Russian Academy of Sciences
Email: ms.kadaver@mail.ru
俄罗斯联邦, Moscow, 119334
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