Neuropeptide cycloprolylglycine increases the levels of brain-derived neurotrophic factor in neuronal cells
- Авторы: Gudasheva T.A.1, Koliasnikova K.N.1, Antipova T.A.1, Seredenin S.B.1
-
Учреждения:
- Zakusov Research Institute of Pharmacology
- Выпуск: Том 469, № 1 (2016)
- Страницы: 273-276
- Раздел: Biochemistry, Biophysics, and Molecular Biology
- URL: https://journals.rcsi.science/1607-6729/article/view/211419
- DOI: https://doi.org/10.1134/S1607672916040104
- ID: 211419
Цитировать
Аннотация
It was shown for the first time that the endogenous cyclic dipeptide cycloprolylglycine (CPG) at concentrations of 10–7 and 10–3 M and piracetam at a concentration of 10–3 M increased the content of brainderived neurotrophic factor (BDNF) in the culture of neuronal cells in normal state and under conditions of glutamate and 6-oxydopamine neurotoxicity. This may indicate the possible involvement of BDNF in the mechanism of action of neuropeptide CPG and piracetam.
Об авторах
T. Gudasheva
Zakusov Research Institute of Pharmacology
Автор, ответственный за переписку.
Email: tata-sosnovka@mail.ru
Россия, ul. Baltiiskaya 8, Moscow, 125315
K. Koliasnikova
Zakusov Research Institute of Pharmacology
Email: tata-sosnovka@mail.ru
Россия, ul. Baltiiskaya 8, Moscow, 125315
T. Antipova
Zakusov Research Institute of Pharmacology
Email: tata-sosnovka@mail.ru
Россия, ul. Baltiiskaya 8, Moscow, 125315
S. Seredenin
Zakusov Research Institute of Pharmacology
Email: tata-sosnovka@mail.ru
Россия, ul. Baltiiskaya 8, Moscow, 125315
Дополнительные файлы
