Мақаланы E-mail арқылы жіберу Potassium Salt of Fullerenylpenta-N-Dihydroxytyrosine Effects on Type 2 Diabetes Mellitus Therapeutic Targets
- Авторлар: Soldatova Y.V.1,2, Kotelnikova R.A.1, Zhilenkov A.V.1, Faingold I.I.1,2, Troshin P.A.1,3, Kozlova M.A.2, Areshidze D.A.1,2, Aldoshin S.M.1
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Мекемелер:
- Institute of Problems of Chemical Physics, Russian Academy of Sciences
- Moscow Region State University
- Skolkovo Institute of Science and Technology
- Шығарылым: Том 488, № 1 (2019)
- Беттер: 320-323
- Бөлім: Biochemistry, Biophysics, and Molecular Biology
- URL: https://journals.rcsi.science/1607-6729/article/view/213087
- DOI: https://doi.org/10.1134/S1607672919050089
- ID: 213087
Дәйексөз келтіру
Ашық рұқсат
Рұқсат берілді
Тек жазылушылар үшін
Аннотация
It was shown for the first time that pentaamino acid derivative of fullerene C60 (potassium salt of fullerenylpenta-N-dihydroxytyrosine) affects three targets of type 2 diabetes mellitus. It competitively inhibits the enzymes aldose reductase and sorbitol dehydrogenase and also has an antiglycation effect on bovine serum albumin. The inhibition constants for these enzymes were calculated.
Авторлар туралы
Yu. Soldatova
Institute of Problems of Chemical Physics, Russian Academy of Sciences; Moscow Region State University
Хат алмасуға жауапты Автор.
Email: soldatovayv@gmail.com
Ресей, Chernogolovka, Moscow oblast, 142432; Moscow
R. Kotelnikova
Institute of Problems of Chemical Physics, Russian Academy of Sciences
Email: soldatovayv@gmail.com
Ресей, Chernogolovka, Moscow oblast, 142432
A. Zhilenkov
Institute of Problems of Chemical Physics, Russian Academy of Sciences
Email: soldatovayv@gmail.com
Ресей, Chernogolovka, Moscow oblast, 142432
I. Faingold
Institute of Problems of Chemical Physics, Russian Academy of Sciences; Moscow Region State University
Email: soldatovayv@gmail.com
Ресей, Chernogolovka, Moscow oblast, 142432; Moscow
P. Troshin
Institute of Problems of Chemical Physics, Russian Academy of Sciences; Skolkovo Institute of Science and Technology
Email: soldatovayv@gmail.com
Ресей, Chernogolovka, Moscow oblast, 142432; Moscow, 143025
M. Kozlova
Moscow Region State University
Email: soldatovayv@gmail.com
Ресей, Moscow
D. Areshidze
Institute of Problems of Chemical Physics, Russian Academy of Sciences; Moscow Region State University
Email: soldatovayv@gmail.com
Ресей, Chernogolovka, Moscow oblast, 142432; Moscow
S. Aldoshin
Institute of Problems of Chemical Physics, Russian Academy of Sciences
Email: soldatovayv@gmail.com
Ресей, Chernogolovka, Moscow oblast, 142432
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