电邮这篇文章 Potassium Salt of Fullerenylpenta-N-Dihydroxytyrosine Effects on Type 2 Diabetes Mellitus Therapeutic Targets
- 作者: Soldatova Y.V.1,2, Kotelnikova R.A.1, Zhilenkov A.V.1, Faingold I.I.1,2, Troshin P.A.1,3, Kozlova M.A.2, Areshidze D.A.1,2, Aldoshin S.M.1
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隶属关系:
- Institute of Problems of Chemical Physics, Russian Academy of Sciences
- Moscow Region State University
- Skolkovo Institute of Science and Technology
- 期: 卷 488, 编号 1 (2019)
- 页面: 320-323
- 栏目: Biochemistry, Biophysics, and Molecular Biology
- URL: https://journals.rcsi.science/1607-6729/article/view/213087
- DOI: https://doi.org/10.1134/S1607672919050089
- ID: 213087
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详细
It was shown for the first time that pentaamino acid derivative of fullerene C60 (potassium salt of fullerenylpenta-N-dihydroxytyrosine) affects three targets of type 2 diabetes mellitus. It competitively inhibits the enzymes aldose reductase and sorbitol dehydrogenase and also has an antiglycation effect on bovine serum albumin. The inhibition constants for these enzymes were calculated.
作者简介
Yu. Soldatova
Institute of Problems of Chemical Physics, Russian Academy of Sciences; Moscow Region State University
编辑信件的主要联系方式.
Email: soldatovayv@gmail.com
俄罗斯联邦, Chernogolovka, Moscow oblast, 142432; Moscow
R. Kotelnikova
Institute of Problems of Chemical Physics, Russian Academy of Sciences
Email: soldatovayv@gmail.com
俄罗斯联邦, Chernogolovka, Moscow oblast, 142432
A. Zhilenkov
Institute of Problems of Chemical Physics, Russian Academy of Sciences
Email: soldatovayv@gmail.com
俄罗斯联邦, Chernogolovka, Moscow oblast, 142432
I. Faingold
Institute of Problems of Chemical Physics, Russian Academy of Sciences; Moscow Region State University
Email: soldatovayv@gmail.com
俄罗斯联邦, Chernogolovka, Moscow oblast, 142432; Moscow
P. Troshin
Institute of Problems of Chemical Physics, Russian Academy of Sciences; Skolkovo Institute of Science and Technology
Email: soldatovayv@gmail.com
俄罗斯联邦, Chernogolovka, Moscow oblast, 142432; Moscow, 143025
M. Kozlova
Moscow Region State University
Email: soldatovayv@gmail.com
俄罗斯联邦, Moscow
D. Areshidze
Institute of Problems of Chemical Physics, Russian Academy of Sciences; Moscow Region State University
Email: soldatovayv@gmail.com
俄罗斯联邦, Chernogolovka, Moscow oblast, 142432; Moscow
S. Aldoshin
Institute of Problems of Chemical Physics, Russian Academy of Sciences
Email: soldatovayv@gmail.com
俄罗斯联邦, Chernogolovka, Moscow oblast, 142432
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