Adsorption of viral particles from the blood plasma of patients with viral hepatitis on nanodiamonds
- Авторы: Baron A.V.1,2, Osipov N.V.3, Yashchenko S.V.3, Kokotukha Y.A.3, Baron I.J.4, Puzyr A.P.1, Olkhovskiy I.A.5,6, Bondar V.S.1
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Учреждения:
- Institute of Biophysics, Siberian Branch
- Siberian Federal University
- Krasnoyarsk Regional Center for Prevention and Control of AIDS
- Voino-Yasenetskii State Medical University
- Krasnoyarsk Branch of Hematology Research Center
- Krasnoyarsk Research Center, Siberian Branch
- Выпуск: Том 469, № 1 (2016)
- Страницы: 244-246
- Раздел: Biochemistry, Biophysics, and Molecular Biology
- URL: https://journals.rcsi.science/1607-6729/article/view/211375
- DOI: https://doi.org/10.1134/S1607672916040037
- ID: 211375
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Аннотация
Adsorption of viral particles from the blood plasma of patients with viral hepatitis B and C on modified nanodiamonds (MNDs) was shown in the in vitro experiments. PCR method showed the treatment of plasma with MNDs leads to a decrease in the viral load by 2–3 orders of magnitude or more in both cases studied. These results make it possible to predict the applicability of MNDs for the development of new technologies of hemodialysis and plasmapheresis for binding and removal of viral particles from the blood of infected patients.
Об авторах
A. Baron
Institute of Biophysics, Siberian Branch; Siberian Federal University
Автор, ответственный за переписку.
Email: alexeybaron@mail.ru
Россия, Akademgorodok, Krasnoyarsk, 660036; Svobodnyi pr. 79, Krasnoyarsk, 660041
N. Osipov
Krasnoyarsk Regional Center for Prevention and Control of AIDS
Email: alexeybaron@mail.ru
Россия, ul. Karla Marksa 47, Krasnoyarsk, 660049
S. Yashchenko
Krasnoyarsk Regional Center for Prevention and Control of AIDS
Email: alexeybaron@mail.ru
Россия, ul. Karla Marksa 47, Krasnoyarsk, 660049
Yu. Kokotukha
Krasnoyarsk Regional Center for Prevention and Control of AIDS
Email: alexeybaron@mail.ru
Россия, ul. Karla Marksa 47, Krasnoyarsk, 660049
I. Baron
Voino-Yasenetskii State Medical University
Email: alexeybaron@mail.ru
Россия, ul. Partizana Zheleznyaka 1, Krasnoyarsk, 660022
A. Puzyr
Institute of Biophysics, Siberian Branch
Email: alexeybaron@mail.ru
Россия, Akademgorodok, Krasnoyarsk, 660036
I. Olkhovskiy
Krasnoyarsk Branch of Hematology Research Center; Krasnoyarsk Research Center, Siberian Branch
Email: alexeybaron@mail.ru
Россия, Krasnoyarsk; Krasnoyarsk, 630036
V. Bondar
Institute of Biophysics, Siberian Branch
Email: alexeybaron@mail.ru
Россия, Akademgorodok, Krasnoyarsk, 660036
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