Adsorption of viral particles from the blood plasma of patients with viral hepatitis on nanodiamonds


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Adsorption of viral particles from the blood plasma of patients with viral hepatitis B and C on modified nanodiamonds (MNDs) was shown in the in vitro experiments. PCR method showed the treatment of plasma with MNDs leads to a decrease in the viral load by 2–3 orders of magnitude or more in both cases studied. These results make it possible to predict the applicability of MNDs for the development of new technologies of hemodialysis and plasmapheresis for binding and removal of viral particles from the blood of infected patients.

作者简介

A. Baron

Institute of Biophysics, Siberian Branch; Siberian Federal University

编辑信件的主要联系方式.
Email: alexeybaron@mail.ru
俄罗斯联邦, Akademgorodok, Krasnoyarsk, 660036; Svobodnyi pr. 79, Krasnoyarsk, 660041

N. Osipov

Krasnoyarsk Regional Center for Prevention and Control of AIDS

Email: alexeybaron@mail.ru
俄罗斯联邦, ul. Karla Marksa 47, Krasnoyarsk, 660049

S. Yashchenko

Krasnoyarsk Regional Center for Prevention and Control of AIDS

Email: alexeybaron@mail.ru
俄罗斯联邦, ul. Karla Marksa 47, Krasnoyarsk, 660049

Yu. Kokotukha

Krasnoyarsk Regional Center for Prevention and Control of AIDS

Email: alexeybaron@mail.ru
俄罗斯联邦, ul. Karla Marksa 47, Krasnoyarsk, 660049

I. Baron

Voino-Yasenetskii State Medical University

Email: alexeybaron@mail.ru
俄罗斯联邦, ul. Partizana Zheleznyaka 1, Krasnoyarsk, 660022

A. Puzyr

Institute of Biophysics, Siberian Branch

Email: alexeybaron@mail.ru
俄罗斯联邦, Akademgorodok, Krasnoyarsk, 660036

I. Olkhovskiy

Krasnoyarsk Branch of Hematology Research Center; Krasnoyarsk Research Center, Siberian Branch

Email: alexeybaron@mail.ru
俄罗斯联邦, Krasnoyarsk; Krasnoyarsk, 630036

V. Bondar

Institute of Biophysics, Siberian Branch

Email: alexeybaron@mail.ru
俄罗斯联邦, Akademgorodok, Krasnoyarsk, 660036

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