Отправить статью по E-mail Optimization of Heterologous Expression of Insulin Receptor-Related Receptor Ectodomain
- Авторы: Mozhaev A.A.1,2, Orsa A.N.1, Deyev I.E.1, Shvets V.I.3, Petrenko A.G.1
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Учреждения:
- Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences
- Shubnikov Institute of Crystallography, Crystallography and Photonics Federal Research Center, Russian Academy of Sciences
- Institute of Fine Chemical Technology, Russian Technological University (MIREA)
- Выпуск: Том 485, № 1 (2019)
- Страницы: 101-103
- Раздел: Biochemistry, Biophysics, and Molecular Biology
- URL: https://journals.rcsi.science/1607-6729/article/view/212880
- DOI: https://doi.org/10.1134/S1607672919020017
- ID: 212880
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Аннотация
In this paper, we present an approach to optimize the heterologous expression of the receptor tyrosine kinase IRR, which further simplifies the purification of the IRR from the medium and increases the final yield. The approach proposed by us can find application in the biotechnological production of other large-scale recombinant proteins produced for medical purposes.
Об авторах
A. Mozhaev
Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences; Shubnikov Institute of Crystallography, Crystallographyand Photonics Federal Research Center, Russian Academy
of Sciences
Автор, ответственный за переписку.
Email: a.a.mozhaev@gmail.com
Россия, Moscow, 117997; Moscow, 117333
A. Orsa
Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences
Email: a.a.mozhaev@gmail.com
Россия, Moscow, 117997
I. Deyev
Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences
Email: a.a.mozhaev@gmail.com
Россия, Moscow, 117997
V. Shvets
Institute of Fine Chemical Technology, Russian Technological University (MIREA)
Email: a.a.mozhaev@gmail.com
Россия, Moscow, 117571
A. Petrenko
Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences
Email: a.a.mozhaev@gmail.com
Россия, Moscow, 117997
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