Optimization of Heterologous Expression of Insulin Receptor-Related Receptor Ectodomain
- 作者: Mozhaev A.A.1,2, Orsa A.N.1, Deyev I.E.1, Shvets V.I.3, Petrenko A.G.1
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隶属关系:
- Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences
- Shubnikov Institute of Crystallography, Crystallography and Photonics Federal Research Center, Russian Academy of Sciences
- Institute of Fine Chemical Technology, Russian Technological University (MIREA)
- 期: 卷 485, 编号 1 (2019)
- 页面: 101-103
- 栏目: Biochemistry, Biophysics, and Molecular Biology
- URL: https://journals.rcsi.science/1607-6729/article/view/212880
- DOI: https://doi.org/10.1134/S1607672919020017
- ID: 212880
如何引用文章
详细
In this paper, we present an approach to optimize the heterologous expression of the receptor tyrosine kinase IRR, which further simplifies the purification of the IRR from the medium and increases the final yield. The approach proposed by us can find application in the biotechnological production of other large-scale recombinant proteins produced for medical purposes.
作者简介
A. Mozhaev
Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences; Shubnikov Institute of Crystallography, Crystallographyand Photonics Federal Research Center, Russian Academy
of Sciences
编辑信件的主要联系方式.
Email: a.a.mozhaev@gmail.com
俄罗斯联邦, Moscow, 117997; Moscow, 117333
A. Orsa
Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences
Email: a.a.mozhaev@gmail.com
俄罗斯联邦, Moscow, 117997
I. Deyev
Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences
Email: a.a.mozhaev@gmail.com
俄罗斯联邦, Moscow, 117997
V. Shvets
Institute of Fine Chemical Technology, Russian Technological University (MIREA)
Email: a.a.mozhaev@gmail.com
俄罗斯联邦, Moscow, 117571
A. Petrenko
Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences
Email: a.a.mozhaev@gmail.com
俄罗斯联邦, Moscow, 117997
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