Kinetic Instability of Zero Steady State As a Fundamental Cause of Low Efficiency of Chemotherapy of Cancer
- Авторы: Varfolomeev S.D.1,2, Lukovenkov A.V.1
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Учреждения:
- Emanuel Institute of Biochemical Physics
- Faculty of Chemistry, Faculty of Chemistry
- Выпуск: Том 483, № 1 (2018)
- Страницы: 309-312
- Раздел: Biochemistry, Biophysics, and Molecular Biology
- URL: https://journals.rcsi.science/1607-6729/article/view/212524
- DOI: https://doi.org/10.1134/S1607672918060030
- ID: 212524
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Аннотация
Using mathematical modeling of the process of cancer treatment by the classical chemotherapy methods and therapy with biological agents, the effect of the kinetic parameters of the model on the final outcome of treatment was studied. It is established that the complete cure (i.e., the formation of a stable steady state with a zero number of cancer cells) cannot be reached by means of only classical chemotherapy.
Об авторах
S. Varfolomeev
Emanuel Institute of Biochemical Physics; Faculty of Chemistry, Faculty of Chemistry
Email: luks.mipt@gmail.com
Россия, ul. Kosygina 4, Moscow, 119334; Moscow, 119991
A. Lukovenkov
Emanuel Institute of Biochemical Physics
Автор, ответственный за переписку.
Email: luks.mipt@gmail.com
Россия, ul. Kosygina 4, Moscow, 119334
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