Kinetic Instability of Zero Steady State As a Fundamental Cause of Low Efficiency of Chemotherapy of Cancer


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Resumo

Using mathematical modeling of the process of cancer treatment by the classical chemotherapy methods and therapy with biological agents, the effect of the kinetic parameters of the model on the final outcome of treatment was studied. It is established that the complete cure (i.e., the formation of a stable steady state with a zero number of cancer cells) cannot be reached by means of only classical chemotherapy.

Sobre autores

S. Varfolomeev

Emanuel Institute of Biochemical Physics; Faculty of Chemistry, Faculty of Chemistry

Email: luks.mipt@gmail.com
Rússia, ul. Kosygina 4, Moscow, 119334; Moscow, 119991

A. Lukovenkov

Emanuel Institute of Biochemical Physics

Autor responsável pela correspondência
Email: luks.mipt@gmail.com
Rússia, ul. Kosygina 4, Moscow, 119334

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