Multiple cylindroma of the scalp

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详细

Cylindroma is a rare benign tumor derived from the skin appendages, its typical localization is head and neck. The histogenesis of the disease is unknown, cylindromas are thought to develop from the epithelial ducts of the eccrine or apocrine glands, or represent a neoplastic proliferation of epithelial stem cells.

The clinical presentation of the disease includes single or multiple smooth nodules and nodes of a pale pink color. Branching vessels are often visualized on their surface.

There are two types of this tumor: sporadic genetically not determined сylindroma and inherited in an autosomal dominant manner multiple сylindroma.

Multiple cylindroma may cause a lesion on the scalp that looks like a turban, due to the fusion and an increasing size of the nodules. Therefore, cylindroma are sometimes called a turban tumor.

The treatment of multiple cylindroma is a serious interdisciplinary problem due to the large area of the lesion, abundant blood supply to the scalp and the tendency of the disease to recur. The treatment methods described in the literature include traditional surgical excision, electrocoagulation, laser, Mohs micrographic surgery.

In this article we present a rare clinical case of a young male diagnosed with multiple cylindroma.

作者简介

Ekaterina Vertieva

I.M. Sechenov First Moscow State Medical University (Sechenov University)

编辑信件的主要联系方式.
Email: ivertieva@gmail.com
ORCID iD: 0000-0002-1088-2911
SPIN 代码: 3712-8453

MD, Cand. Sci. (Med.)

俄罗斯联邦, Moscow

Kseniya Teplyakova

I.M. Sechenov First Moscow State Medical University (Sechenov University)

Email: hvpvea@gmail.com
ORCID iD: 0000-0002-0428-5627
SPIN 代码: 5983-9344

Graduate Student

俄罗斯联邦, Moscow

参考

  1. Kuklani RM, Glavin FL, Bhattacharyya I. Malignant cylindroma of the scalp arising in a setting of multiple cylindromatosis: a case report. Head Neck Pathol. 2009;3(4):315–319. doi: 10.1007/s12105-009-0138-x
  2. Chauhan DS, Guruprasad Y. Dermal cylindroma of the scalp. Natl J Maxillofac Surg. 2012;3(1):59–61. doi: 10.4103/0975-5950.102163
  3. Munger BL, Graham JH, Helwig EB. Ultrastructure and histochemical characteristics of dermal eccrine cylindroma (turban tumor). J Invest Dermatol. 1962;39:577–595.
  4. Tunggal L, Ravaux J, Pesch M, at al. Defective laminin 5 processing in cylindroma cells. Am J Pathol. 2002;160(2):459–468. doi: 10.1016/S0002-9440(10)64865-1
  5. Massoumi R, Podda M, Fässler R, Paus R. Cylindroma as tumor of hair follicle origin. J Invest Dermatol. 2006;126(5):1182–1184. doi: 10.1038/sj.jid.5700218
  6. Adam MP, Ardinger HH, Pagon RA, et al., editors.GeneReviews [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2021. Available from: https://www.ncbi.nlm.nih.gov/books/NBK1116/. Accessed:15.11.2021.
  7. Schwarz D, Drebber U, Ortmann M, Anagiotos A. Benign cylindroma: a rare differential diagnosis of external ear canal tumour. BMJ Case Rep. 2016;2016:bcr2015212035. doi: 10.1136/bcr-2015-212035
  8. Gupta R, Jain R, Sood S, Mohan H. Dermal cylindroma presenting as mass lesion in superomedial orbit. Indian J Ophthalmol. 2003;51(3):257–259.
  9. Miraglia E, Moliterni E, Iacovino C, еt al. Cutaneous manifestations in neurofibromatosis type 1. ClinTer. 2020;171(5):e371–e377. doi: 10.7417/CT.2020.2242

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1. JATS XML
2. Fig. 1. Patient M., 27 years old. The clinical and morphological presentations of multiple cylindroma: а ― on the skin of the scalp, a node of dense consistency with a size of 5 cm, hemispherical shape, with a smooth surface and clear boundaries, pale pink; branching vessels are visible on the surface; б, в ― on the skin of the scalp, many monomorphic nodules and nodes ranging in size from 5 mm to 3 cm, dense consistency, hemispherical shape, with a smooth surface, clear boundaries, ranging in color from pale pink to reddish.

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3. Fig. 2. Patient M., 27 years old. Dermatoscopic features: neoangiogenesis, branching vessels. The dermoscopic pattern is typical for the diagnosis of multiple scalp cylindroma.

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