Successful treatment of pyoderma gangrenosum in a patient winh ulcerative colitis and COVID-19 infection: case report
- Authors: Teplyuk N.P.1, Grabovskaya O.V.1, Kusraeva D.T.1, Grekova E.V.1, Koriakin D.A.1, Kostenko A.Y.1
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Affiliations:
- I.M. Sechenov First Moscow State Medical University (Sechenov University)
- Issue: Vol 25, No 5 (2022)
- Pages: 373-380
- Section: DERMATOLOGY
- URL: https://journals.rcsi.science/1560-9588/article/view/233229
- DOI: https://doi.org/10.17816/dv111864
- ID: 233229
Cite item
Abstract
Pyoderma gangrenosum is a rare inflammatory neutrophilic dermatosis, which causes ulceration of the skin. The condition is commonly associated with underlying systemic disorders such as inflammatory bowel disease, arthritis, and hematological disorders. Herein, we describe the case of a familiar association between pyoderma gangrenosum and ulcerative colitis complicated by the newly COVID-19 infection.
It is of particular clinical interest to address pyoderma gangrenosum lesions with concurrent treatment of associated disorders that may have influence on the course of the ulcer. Moreover, the therapy should cover as many diseases as possible while not being excessive to minimize possible side effects.
Thus, the selection of treatment that spans mutual pathophysiological features of all comorbidities represents the best option to make when handling pyoderma gangrenosum patients.
We present a case of the development of gangrenous pyoderma against the background of ulcerative colitis complicated by the new coronavirus infection COVID-19, which will raise awareness of gangrenous pyoderma as a relatively rare cause of ulcerative necrotic skin lesions, which can easily be confused with an infectious process.
Of particular clinical importance in the conditions of the COVID-19 pandemic is the correct treatment of gangrenous pyoderma. Only an integrated approach can give a positive result from the therapy.
Keywords
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##article.viewOnOriginalSite##About the authors
Nataliya P. Teplyuk
I.M. Sechenov First Moscow State Medical University (Sechenov University)
Email: Teplyukn@gmail.com
ORCID iD: 0000-0002-5800-4800
SPIN-code: 8013-3256
MD, Dr. Sci. (Med.), Professor
Russian Federation, MoscowOlga V. Grabovskaya
I.M. Sechenov First Moscow State Medical University (Sechenov University)
Email: olgadoctor2013@yandex.ru
ORCID iD: 0000-0002-5259-7481
SPIN-code: 1843-1090
MD, Cand. Sci. (Med.), Associate Professor
Russian Federation, MoscowDiana T. Kusraeva
I.M. Sechenov First Moscow State Medical University (Sechenov University)
Author for correspondence.
Email: kysra1992@mail.ru
ORCID iD: 0000-0002-5633-7986
SPIN-code: 1478-3503
Postgraduate Student
Russian Federation, 4 build. 1, Bolshaya Pirogovskaya str., Moscow, 119991Ekaterina V. Grekova
I.M. Sechenov First Moscow State Medical University (Sechenov University)
Email: grekova_kate@mail.ru
ORCID iD: 0000-0002-7968-9829
SPIN-code: 8028-5545
MD, Cand. Sci. (Med.)
Russian Federation, MoscowDanila A. Koriakin
I.M. Sechenov First Moscow State Medical University (Sechenov University)
Email: danila110920021@gmail.com
ORCID iD: 0000-0003-3619-206X
Student
Russian Federation, MoscowAnastasia Yu. Kostenko
I.M. Sechenov First Moscow State Medical University (Sechenov University)
Email: anastasiya.k9716@gmail.com
ORCID iD: 0000-0002-4115-540X
MD
Russian Federation, MoscowReferences
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