Acanthosis nigricans


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Abstract

Clinical and morphological characteristics of acanthosis nigricans (pigmented papillary degeneration of the skin), referred to a heterogeneous group of papillomatous keratoses and characterized by villous papillomatous growth and hyperpigmentation of the skin, are presented. Acanthosis nigricans is a rare disease and is often a “marker” of visceral diseases, such as polycystic ovaries, insulin-resistant diabetes mellitus, obesity, malignant tumors. Published data on the pathogenesis, clinical forms, and histological picture of the disease are presented. A clinical observation of benign acanthosis nigricans in a young patient is presented.

About the authors

Elena S. Snarskaya

I.M. Setchenov First Moscow State Medical University

Email: snarskaya-dok@mail.ru
MD, PhD, DSc, prof. 119991, Moscow, Russia

P. A Kochubeeva

Ramenskoe Central Clinical Hospital

Dermato-Venereological Department 140100, Ramenskoe, Moscow Region

References

  1. Бутов Ю.С., Азимова Т.В., Анисимова Т.В., Чумаков А.М. Злокачественная форма черного акантоза, развившаяся у больного раком мочевого пузыря. Российский журнал кожных и венерических болезней. 2001; 2: 4-5.
  2. Adigun C.G., Pandya A.G. Improvement of idiopathic acanthosis nigricans with a triple combination depigmenting cream. J. Eur. Acad. Dermatol. Venerol. 2009; 23(4): 486-7.
  3. Higgins S.P., Freemark M., Prose N.S. Acanthosis nigricans: a practical approach to evaluation and management. Dermatol. Online J. 2008; 14(9): 2.
  4. Garofalo L., Biscozzi A.M., Mastrandrea V., Bonifazi E. Acanthosis nigricans vulgaris. A marker of hyperinsulinemia. Eur. J. Pediatr. Dermatol. 2003; 13: 85-8.
  5. Elder D.E., Elenitsas R., Johnson B., Murphy G., eds. Lever’s histopathology of the skin. Philadelphia: Lippincott; 2005: 456-7.
  6. Schwartz R.A. Acanthosis nigricans. J. Am. Acad. Dermatol. 1994; 31(1): 1-19.
  7. Schwartz R.A. Acral acanthosis nigricans (acral acanthotic anomaly). J. Am. Acad. Dermatol. 2007; 56(2): 349-50.
  8. Rigel D.S., Jacobs M.I. Malignant acanthosis nigricans:a review. J. Dermatol. Surg. Oncol. 1980; 6(11): 923-7.

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