Email this article Human papillomavirus and its association with oral lichen planus
- Authors: Starshinina V.A.1, Perlamutrov Y.N.1, Olhovskaya K.B.1
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Affiliations:
- Moscow State University of Medicine and Dentistry named after A.I. Evdokimov
- Issue: Vol 26, No 6 (2023)
- Pages: 645-652
- Section: DERMATOLOGY
- URL: https://journals.rcsi.science/1560-9588/article/view/254774
- DOI: https://doi.org/10.17816/dv611050
- ID: 254774
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Abstract
BACKGROUND: Oral lichen planus is a chronic disease with periods of exacerbations and remissions, requiring long-term symptomatic treatment and observation. Dermatosis can occur or worsen in the presence of different triggers, for example, due to the persistence of the human papillomavirus.
AIM: to explore the effect human papillomavirus on the characteristics oral lichen planus.
MATERIALS AND METHODS: 90 patients with oral lichen planus aged from 26 to 73 years (average age 55.61±1.00 years) were examined. Real-time polymerase chain reaction was used to detect human papillomavirus. The need for treatment of caries, Green–Vermillion and complex periodontal indices were used to analysis state of oral hygiene.
RESULTS: Human papillomavirus DNA was detected in 53 (58.88%) cases. Patients of this group were 4 years younger than other study participants; the duration of dermatosis is 2 years longer with a predominance of atrophic/erythematous and erosive/ulcerative forms. It was noted that indexes of caries and the complex periodontal were significantly (p=0,007 and p=0,030 respectively) higher compared to patients without papillomavirus infection.
CONCLUSION: It is found features of oral lichen planus in identifying human papillomavirus: early onset; severe of the disease with predominantly destructive forms; high prevalence of caries and periodontitis.
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##article.viewOnOriginalSite##About the authors
Victoria A. Starshinina
Moscow State University of Medicine and Dentistry named after A.I. Evdokimov
Author for correspondence.
Email: starshinina_v@rambler.ru
ORCID iD: 0000-0001-5171-268X
SPIN-code: 6427-4162
Graduate Student
Russian Federation, 103 Mira avenue, 129085 MoscowYuri N. Perlamutrov
Moscow State University of Medicine and Dentistry named after A.I. Evdokimov
Email: mgmsu-skin@mail.ru
ORCID iD: 0000-0002-4837-8489
SPIN-code: 2330-2758
MD, Dr. Sci. (Med.), Professor
Russian Federation, 103 Mira avenue, 129085 MoscowKira B. Olhovskaya
Moscow State University of Medicine and Dentistry named after A.I. Evdokimov
Email: olhovskaya_kira@mail.ru
ORCID iD: 0000-0003-4920-5288
SPIN-code: 9455-9482
MD, Cand. Sci. (Med.), Associated Professor
Russian Federation, 103 Mira avenue, 129085 MoscowReferences
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